Thymosin alpha‑1 inhibited binding of labelled LKEKK to donor blood T-lymphocytes with a Ki of 2.0 nM.
In plain wordsIn cells, thymosin alpha‑1 blocked the binding of the labelled LKEKK peptide to human T cells.
- Peptide
- Thymosin alpha-1
- Outcome
- Not applicableInhibition of [3H]LKEKK binding by thymosin alpha 1
- Study
humann: not reported in source
Donor blood T-lymphocytes- Outcome group
- Receptor activity and mechanism · Immune and inflammation
- Studied dose
- Dose not stated
Measurements
- Ki
- 2 nM
- inhibition of [3H]LKEKK binding to T-lymphocytes
Source sentences
The binding was inhibited by thymosin-α1, interferon-α2, and cholera toxin B subunit (Ki = 2.0 ± 0.3, 2.2 ± 0.2, and 3.6 ± 0.3 nM, respectively).
1 context sentence(design, population, supporting numbers)
The [3H]LKEKK bound with high affinity (Kd = 3.7 ± 0.3 nM) to donor blood T-lymphocytes.