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Study · Not a test of the peptide alone · 2016

5 results

Neuroprotective effect of epidermal growth factor plus growth hormone-releasing peptide-6 resembles hypothermia in experimental stroke.

Subirós N, Pérez-Saad H, Aldana L, Gibson CL, Borgnakke WS, Garcia-Del-Barco D

Neurological research26 Sept 2016Cited by 8 (Europe PMC)

PMID27665924 (opens in a new tab)DOI10.1080/01616412.2016.1235249 (opens in a new tab)PepBankPUB-27665924
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In gerbils with global ischemia, EGF plus GHRP‑6 produced neurological scores at 48-72 h similar to hypothermia.

    In plain wordsIn gerbils with global ischemia, the combination produced neurological scores similar to hypothermia.

    Peptide
    GHRP-6
    Outcome
    No significant changeNeurological score
    Study

    Mongolian gerbiln: not reported in source

    Global ischemia
    Comparator
    Hypothermia
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    (a) In global ischemia, neurological score at 48-72 h, infarct volume, and neuronal density of hippocampal CA1 zone in gerbils treated with EGF + GHRP-6 were similar to the hypothermia-treated group.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In gerbils with global ischemia, EGF plus GHRP‑6 produced infarct volumes similar to hypothermia.

    In plain wordsIn gerbils with global ischemia, infarct volume with the combination was similar to hypothermia.

    Peptide
    GHRP-6
    Outcome
    No significant changeInfarct volume
    Study

    Mongolian gerbiln: not reported in source

    Global ischemia
    Comparator
    Hypothermia
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    (a) In global ischemia, neurological score at 48-72 h, infarct volume, and neuronal density of hippocampal CA1 zone in gerbils treated with EGF + GHRP-6 were similar to the hypothermia-treated group.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In gerbils with global ischemia, hippocampal CA1 neuronal density with EGF plus GHRP‑6 resembled that with hypothermia.

    In plain wordsIn gerbils, hippocampal neuron density with the combination was similar to hypothermia.

    Peptide
    GHRP-6
    Outcome
    No significant changeHippocampal CA1 neuronal density
    Study

    Mongolian gerbiln: not reported in source

    Global ischemia
    Comparator
    Hypothermia
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    (a) In global ischemia, neurological score at 48-72 h, infarct volume, and neuronal density of hippocampal CA1 zone in gerbils treated with EGF + GHRP-6 were similar to the hypothermia-treated group.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  4. 04AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In rats with focal ischemia, EGF plus GHRP‑6 produced neurological scores similar to hypothermia.

    In plain wordsIn rats with focal ischemia, neurological scores with the combination were similar to hypothermia.

    Peptide
    GHRP-6
    Outcome
    No significant changeNeurological score
    Study

    Wistar ratn: not reported in source

    Focal brain ischemia
    Comparator
    Hypothermia
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    (b) In focal ischemia, the neurologic score and infarct volume of rats receiving EGF + GHRP-6 were also similar to animals in the hypothermia group.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  5. 05AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In rats with focal ischemia, EGF plus GHRP‑6 produced infarct volumes similar to hypothermia.

    In plain wordsIn rats with focal ischemia, infarct volume with the combination was similar to hypothermia.

    Peptide
    GHRP-6
    Outcome
    No significant changeInfarct volume
    Study

    Wistar ratn: not reported in source

    Focal brain ischemia
    Comparator
    Hypothermia
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    (b) In focal ischemia, the neurologic score and infarct volume of rats receiving EGF + GHRP-6 were also similar to animals in the hypothermia group.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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