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Study · Randomized controlled trial · n = 139 · 2017

2 results

Oxytocin conditions trait-based rule adherence.

Gross J, De Dreu CK

Social cognitive and affective neuroscience1 Mar 2017Cited by 10 (Europe PMC)

PMID27664999 (opens in a new tab)PMCIDPMC5390698 (opens in a new tab)DOI10.1093/scan/nsw138 (opens in a new tab)PepBankPUB-27664999
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy participants, intranasal oxytocin increased how often participants violated an arbitrary costly rule versus placebo.

    In plain wordsIn healthy people, oxytocin spray made them break an arbitrary costly rule more often than placebo did.

    Peptide
    Oxytocin
    Outcome
    IncreaseRule violation frequency
    Study

    n = 139

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Under oxytocin, participants violated the rule more often
    1 context sentence
    Summary · context
    Participants (N = 139) self-administered oxytocin or placebo intranasally, and reported their need for structure and approach-avoidance sensitivity.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy participants, the increase in rule violation under oxytocin was larger in those with high need for structure and high approach sensitivity.

    In plain wordsIn healthy people, oxytocin spray led to more rule breaking, especially in those with a high need for structure and high approach sensitivity.

    Peptide
    Oxytocin
    Outcome
    IncreaseRule violation by need for structure and approach sensitivity
    Study

    n = 139

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Under oxytocin, participants violated the rule more often, especially when they had high need for structure and high approach sensitivity.
    1 context sentence
    Summary · context
    Participants (N = 139) self-administered oxytocin or placebo intranasally, and reported their need for structure and approach-avoidance sensitivity.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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