In healthy men, intranasal oxytocin attenuated the N400m effect to world-knowledge incongruent sentences versus placebo.
In plain wordsIn healthy men, oxytocin spray reduced a brain response to sentences that conflict with world knowledge, compared with placebo.
- Peptide
- Oxytocin
- Outcome
- DecreaseN400m semantic integration effect
- Study
n = 45
- Comparator
- Placebo
- Outcome group
- Brain and neuronal activity · Nervous system and cognition
- Studied dose
- Dose not stated · intranasalAs given in this study (human).
Source sentences
Oxytocin administration significantly attenuated the N400m effect at both sensor and cortical source levels throughout the experiment, in a state-like manner.
2 context sentences(design, population, supporting numbers)
The study used a between-participant double-blind randomized placebo-controlled design.
Semantic integration, indexed with magnetoencephalography through the N400m marker, was quantified while 45 healthy male participants listened to sentences that were either congruent or incongruent with facts of the world, after receiving intranasally delivered oxytocin or placebo.