The correlation between plasma levels of oxytocin and betatrophin in non-diabetic and diabetic metabolic syndrome patients: A cross sectional study from Jordan.

Al-Rawashdeh A, Kasabri V, Bulatova N, Akour A, Zayed A, Momani M, Khawaja N, Bustanji H, Hyasat D

Diabetes & metabolic syndrome22 Aug 2016Cited by 19 (Europe PMC)

PMID27578619DOI10.1016/j.dsx.2016.08.008PepBankPUB-27578619

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01HumanEndogenous levelObservational studyOther
In patients with metabolic syndrome, plasma oxytocin was lower in those with prediabetes or type 2 diabetes than in those without diabetes.
In plain wordsIn people with metabolic syndrome, the body's own oxytocin level was lower with prediabetes or type 2 diabetes than without diabetes.
Peptide
Oxytocin
Outcome
DecreasePlasma oxytocin in MS-pre/T2DM versus MS controls
Study
n = 158
Comparator
Metabolic syndrome patients without diabetes
Outcome group
Hormone levels · Metabolic and weight
Measurements
OXT concentration
1222.46 pg/mL
MS-pre/T2DM
OXT concentration
2323.42 pg/mL
MS control
Source sentences
Summary
On the contrary, OXT concentrations were decreased (P<0.001) in the MS-pre/T2DM patients (1222.46±514.55pg/mL) as compared to the MS control subjects (2323.42±848.68pg/mL).
1 context sentence(design, population, supporting numbers)
Summary · context
The aim was to assess correlations between plasma betatrophin and OXT levels in MS-diabetic or prediabetic (N=89) as compared to MS-non-diabetic (N=69) patients.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2757861901
02HumanEndogenous levelObservational studyOther
In patients with metabolic syndrome, plasma oxytocin correlated negatively with plasma betatrophin.
In plain wordsIn people with metabolic syndrome, higher levels of the body's own oxytocin were linked to lower betatrophin levels.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of plasma oxytocin with betatrophin
Study
n = 158
Outcome group
Hormone levels · Metabolic and weight
Measurements
Correlation r
−0.492
OXT with betatrophin
Source sentences
Summary
OXT concentration correlated negatively (r=-0.492, P<0.001)
1 context sentence(design, population, supporting numbers)
Summary · context
The aim was to assess correlations between plasma betatrophin and OXT levels in MS-diabetic or prediabetic (N=89) as compared to MS-non-diabetic (N=69) patients.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2757861902
03HumanEndogenous levelObservational studyOther
In patients with metabolic syndrome, HbA1c was inversely correlated with plasma oxytocin.
In plain wordsIn people with metabolic syndrome, higher HbA1c was linked to lower levels of the body's own oxytocin.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of plasma oxytocin with HbA1c
Study
n = 158
Outcome group
Hormone levels · Metabolic and weight
Source sentences
Summary
HbA1c and FPG correlated positively with betatrophin plasma levels (P<0.001), but were inversely correlated with OXT levels (P<0.001) in the total sample.
1 context sentence(design, population, supporting numbers)
Summary · context
The aim was to assess correlations between plasma betatrophin and OXT levels in MS-diabetic or prediabetic (N=89) as compared to MS-non-diabetic (N=69) patients.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2757861903
04HumanEndogenous levelObservational studyOther
In patients with metabolic syndrome, fasting plasma glucose was inversely correlated with plasma oxytocin.
In plain wordsIn people with metabolic syndrome, higher fasting blood glucose was linked to lower levels of the body's own oxytocin.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of plasma oxytocin with fasting plasma glucose
Study
n = 158
Outcome group
Hormone levels · Metabolic and weight
Source sentences
Summary
HbA1c and FPG correlated positively with betatrophin plasma levels (P<0.001), but were inversely correlated with OXT levels (P<0.001) in the total sample.
1 context sentence(design, population, supporting numbers)
Summary · context
The aim was to assess correlations between plasma betatrophin and OXT levels in MS-diabetic or prediabetic (N=89) as compared to MS-non-diabetic (N=69) patients.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2757861904

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 01:30 UTC
Study results updated
Version 1
9 Oct 2026, 02:50 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.