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Study · Randomized controlled trial · 2016

2 results

Oxytocin enhances inter-brain synchrony during social coordination in male adults.

Mu Y, Guo C, Han S

Social cognitive and affective neuroscience10 Aug 2016Cited by 111 (Europe PMC)

PMID27510498 (opens in a new tab)PMCIDPMC5141958 (opens in a new tab)DOI10.1093/scan/nsw106 (opens in a new tab)PepBankPUB-27510498
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Summary

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Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In male dyads, intranasal oxytocin versus placebo improved interpersonal behavioural synchrony in both the coordination and control tasks.

    In plain wordsIn pairs of men, nasal oxytocin improved how well partners synchronised their behaviour, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseInterpersonal behavioural synchrony in male dyads
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Experiment 2, using a double blind, placebo-controlled between-subjects design, revealed that intranasal OT vs placebo administration in male dyads improved interpersonal behavioral synchrony in both the coordination and control tasks but specifically enhanced alpha-band inter-brain neural oscillati…
    1 context sentence
    Summary · context
    Electroencephalography (EEG) was recorded simultaneously from a dyad to examine OT effects on inter-brain synchrony of neural activity during interpersonal coordination.
  2. 02HumanRandomized controlled trialMechanism

    In male dyads, intranasal oxytocin versus placebo specifically enhanced alpha-band inter-brain neural oscillations during the coordination task.

    In plain wordsIn pairs of men, nasal oxytocin increased the matching of brain rhythms between partners during coordination, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseAlpha-band inter-brain neural oscillations during coordination
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Experiment 2, using a double blind, placebo-controlled between-subjects design, revealed that intranasal OT vs placebo administration in male dyads improved interpersonal behavioral synchrony in both the coordination and control tasks but specifically enhanced alpha-band inter-brain neural oscillati…
    1 context sentence
    Summary · context
    Electroencephalography (EEG) was recorded simultaneously from a dyad to examine OT effects on inter-brain synchrony of neural activity during interpersonal coordination.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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