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Study · Randomized controlled trial · 2016

3 results

Fear or greed? Oxytocin regulates inter-individual conflict by enhancing fear in men.

Zheng H, Kendrick KM, Yu R

Hormones and behavior18 Jul 2016Cited by 9 (Europe PMC)

PMID27444251 (opens in a new tab)DOI10.1016/j.yhbeh.2016.07.003 (opens in a new tab)PepBankPUB-27444251
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In men, oxytocin-exposed participants were less cooperative in general than the placebo group in a modified Prisoner's dilemma game.

    In plain wordsIn men playing a cooperation game, oxytocin made participants less cooperative than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseCooperation in a Prisoner's dilemma game
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Results showed that compared with the placebo group, oxytocin-exposed participants were less cooperative in general.
    1 context sentence
    Summary · context
    Using a double-blind placebo-controlled design combined with a modified Prisoner's dilemma game (PDG), we examined the effect of oxytocin on social motivations in inter-individual conflict in men.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In men, oxytocin amplified the effect of fear on defection in a modified Prisoner's dilemma game.

    In plain wordsIn men playing a cooperation game, oxytocin strengthened the effect of fear on choosing not to cooperate.

    Peptide
    Oxytocin
    Outcome
    IncreaseEffect of fear on defection
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Specifically, oxytocin amplified the effect of fear on defection
    1 context sentence
    Summary · context
    Using a double-blind placebo-controlled design combined with a modified Prisoner's dilemma game (PDG), we examined the effect of oxytocin on social motivations in inter-individual conflict in men.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In men, oxytocin did not influence the effect of greed on defection in a modified Prisoner's dilemma game.

    In plain wordsIn men playing a cooperation game, oxytocin did not change the effect of greed on choosing not to cooperate.

    Peptide
    Oxytocin
    Outcome
    No significant changeEffect of greed on defection
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    but did not influence the effect of greed.
    1 context sentence
    Summary · context
    Using a double-blind placebo-controlled design combined with a modified Prisoner's dilemma game (PDG), we examined the effect of oxytocin on social motivations in inter-individual conflict in men.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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