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Study · Not a test of the peptide alone · 2016

1 result

Transcriptional Profiling of Mycobacterium tuberculosis Exposed to In Vitro Lysosomal Stress.

Lin W, de Sessions PF, Teoh GH, Mohamed AN, Zhu YO, Koh VH, Ang ML, Dedon PC, Hibberd ML, Alonso S

Infection and immunity19 Aug 2016Cited by 43 (Europe PMC)

PMID27324481 (opens in a new tab)PMCIDPMC4995911 (opens in a new tab)DOI10.1128/iai.00072-16 (opens in a new tab)PepBankPUB-27324481
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking LL-37.

  1. 01LabNot a test of LL-37 aloneIn vitro (cells)Activity measurement

    In lab tests, an M. tuberculosis ΔRv1258c mutant showed increased susceptibility to killing by LL‑37, which served as a challenge to test the mutant.

    In plain wordsIn lab tests, a tuberculosis bacterium missing one pump gene was killed more easily by LL‑37.

    Peptide
    LL-37
    Outcome
    IncreaseSusceptibility of M. tuberculosis ΔRv1258c mutant to LL-37
    Study

    Mycobacterium tuberculosisn: not reported in source

    In vitro bacterial killing assay with a ΔRv1258c mutant
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    An M. tuberculosis ΔRv1258c mutant was constructed and displayed increased susceptibility to killing by lysosomal SF and the antimicrobial peptide LL-37

    In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking LL-37.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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