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Study · Measured the body's own peptide · 2016

3 results

Effects of resistance training on expression of IGF-I splice variants in younger and older men.

Ahtiainen JP, Hulmi JJ, Lehti M, Kraemer WJ, Nyman K, Selänne H, Alen M, Komulainen J, Kovanen V, Mero AA, Philippou A, Laakkonen EK, Häkkinen K

European journal of sport science27 May 2016Cited by 15 (Europe PMC)

PMID27231807 (opens in a new tab)DOI10.1080/17461391.2016.1185164 (opens in a new tab)PepBankPUB-27231807
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialMechanism

    In older men, the body's own MGF mRNA expression in muscle increased after a resistance exercise bout before resistance training.

    In plain wordsIn older men, the body's own MGF gene activity in muscle rose after a bout of resistance exercise.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA after resistance exercise before training in older men
    Study

    n = 10

    Outcome group
    Exercise and physical function · Musculoskeletal

    Source sentences

    Summary
    except for MGF mRNA expression which was increased (p < .01) following RE before RT in OM.
    1 context sentence
    Summary · context
    Therefore, resistance exercise-induced changes in skeletal muscle IGF-IEa and MGF messenger ribonucleic acid (mRNA), and MGF, Erk1/2, Akt and p70S6K protein expression were investigated before and after 21 weeks of RT in younger (YM, 20-34 yrs., n = 7) and older men (OM, 51-71 yrs., n = 10).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialMechanism

    Skeletal muscle MGF protein levels and MGF mRNA expression were not systematically influenced by resistance exercise or resistance training, apart from the older men's pre-training exercise response.

    In plain wordsIn men, the body's own MGF levels in muscle did not change in a consistent way after exercise or training.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeMGF expression response to resistance exercise and training in other conditions
    Study

    n: not reported in source

    Outcome group
    Exercise and physical function · Musculoskeletal

    Source sentences

    Summary
    The muscle proteins or mRNAs of interest were not systematically influenced by the REs or RT
    1 context sentence
    Summary · context
    Therefore, resistance exercise-induced changes in skeletal muscle IGF-IEa and MGF messenger ribonucleic acid (mRNA), and MGF, Erk1/2, Akt and p70S6K protein expression were investigated before and after 21 weeks of RT in younger (YM, 20-34 yrs., n = 7) and older men (OM, 51-71 yrs., n = 10).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelNon-randomized trialMechanism

    Basal levels and exercise-induced responses of muscle MGF protein and MGF mRNA did not differ between younger and older men.

    In plain wordsThe body's own MGF levels in muscle did not differ between younger and older men.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeMGF expression, younger versus older men
    Study

    n: not reported in source

    Comparator
    Younger men
    Outcome group
    Exercise and physical function · Musculoskeletal

    Source sentences

    Summary
    No differences were observed between YM and OM in any variables.
    2 context sentences
    Summary · context
    basal levels or RE-induced responses in skeletal muscle MGF, Erk1/2, Akt and p70S6K protein levels or IGF-IEa and MGF mRNA expression did not differ between YM and OM
    Summary · context
    Therefore, resistance exercise-induced changes in skeletal muscle IGF-IEa and MGF messenger ribonucleic acid (mRNA), and MGF, Erk1/2, Akt and p70S6K protein expression were investigated before and after 21 weeks of RT in younger (YM, 20-34 yrs., n = 7) and older men (OM, 51-71 yrs., n = 10).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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