In microvascular endothelial cells under proteolytic and thermal stress, ARA290-elastin-like polypeptide fusion particles prevented cell death better than the peptide alone.
In plain wordsIn cells, particles that carry ARA290 protected blood-vessel cells from dying better than the peptide alone.
- Peptide
- Cibinetide (ARA-290)
- Outcome
- IncreaseMicrovascular cell death prevention, fusion particles versus peptide alone
- Study
n: not reported in source
Microvascular endothelial cells under proteolytic and thermal stress- Comparator
- ARA290 peptide alone
- Outcome group
- Wound healing · Skin and wound
Source sentences
Furthermore, the data strongly suggest these ARA290-functionalized particles were superior to treatment with the peptide alone in preventing microvascular cell death in these conditions.
1 context sentence(design, population, supporting numbers)
Here we demonstrate the advantages of fusing ARA290 to an elastin-like polypeptide (ELP) to salvage microvascular endothelial cells in harsh proteolytic conditions following thermal shock.
In this study, Cibinetide (ARA-290) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cibinetide (ARA-290).