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Study · Animal study (in vivo) · rat · 2016

3 results

Cerebrolysin improves memory and ameliorates neuronal atrophy in spontaneously hypertensive, aged rats.

Solis-Gaspar C, Vazquez-Roque RA, De Jesús Gómez-Villalobos M, Flores G

Synapse (New York, N.Y.)30 May 2016Cited by 30 (Europe PMC)

PMID27164468 (opens in a new tab)DOI10.1002/syn.21912 (opens in a new tab)PepBankPUB-27164468
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In old female hypertensive rats, Cerebrolysin increased pyramidal-neuron dendritic length in the dorsal hippocampal CA1 and prefrontal cortex layers.

    In plain wordsIn rats with hypertension, Cerebrolysin increased dendritic length in hippocampal and prefrontal neurons.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseDendritic length
    Study

    ratn: not reported in source

    Old female spontaneously hypertensive rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · 6 monthsAs given in this study (rat).

    Source sentences

    Summary
    Clearly, SH rats with Cbl showed an increase in the dendritic length and dendritic spine density of pyramidal neurons in the CA1 in the dorsal hippocampus and layers 3 and 5 of the PFC.
    1 context sentence
    Summary · context
    Female SH rats (6 months old) received 6 months of Cbl treatment.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In old female hypertensive rats, Cerebrolysin increased pyramidal-neuron dendritic spine density in the dorsal hippocampal CA1 and prefrontal cortex layers.

    In plain wordsIn rats with hypertension, Cerebrolysin increased dendritic spine density in hippocampal and prefrontal neurons.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseDendritic spine density
    Study

    ratn: not reported in source

    Old female spontaneously hypertensive rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · 6 monthsAs given in this study (rat).

    Source sentences

    Summary
    Clearly, SH rats with Cbl showed an increase in the dendritic length and dendritic spine density of pyramidal neurons in the CA1 in the dorsal hippocampus and layers 3 and 5 of the PFC.
    1 context sentence
    Summary · context
    Female SH rats (6 months old) received 6 months of Cbl treatment.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In old spontaneously hypertensive rats, Cerebrolysin improved memory.

    In plain wordsIn old rats with hypertension, Cerebrolysin improved memory.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseMemory
    Study

    ratn: not reported in source

    Old female spontaneously hypertensive rats
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · 6 monthsAs given in this study (rat).

    Source sentences

    Summary
    Interestingly, Cbl improved memory of the old SH rats.
    1 context sentence
    Summary · context
    Female SH rats (6 months old) received 6 months of Cbl treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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