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Study · Measured the body's own peptide · 2016

3 results

Neuronal activity and the expression of hypothalamic oxytocin and vasopressin in social versus cocaine conditioning.

Liu C, Wang J, Zhan B, Cheng G

Behavioural brain research9 May 2016Cited by 14 (Europe PMC)

PMID27163750 (opens in a new tab)DOI10.1016/j.bbr.2016.05.010 (opens in a new tab)PepBankPUB-27163750
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In ICR mice, hypothalamic oxytocin expression in the paraventricular nucleus was higher after social or cocaine conditioning than in control mice.

    In plain wordsIn mice, the body's own oxytocin in one brain area was higher after social or cocaine conditioning than in control mice.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin expression in the paraventricular nucleus, social or cocaine conditioning versus control
    Study

    mousen: not reported in source

    ICR mice
    Comparator
    Control (CK) group
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Compared to the CK group, the SC or CC group had higher OT expression in the paraventricular nucleus (PVN)
    1 context sentence
    Summary · context
    Here, we investigated the conditioned place preference (CPP) in social (conspecific) vs cocaine conditioning, and the expression of central c-Fos, hypothalamic oxytocin (OT) and vasopressin (AVP) in ICR mice.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In ICR mice, hypothalamic oxytocin expression was lower after concurrent social versus cocaine conditioning than after social conditioning alone.

    In plain wordsIn mice, the body's own oxytocin was lower when social and cocaine conditioning were combined than with social conditioning alone.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin expression, social versus cocaine conditioning compared with social conditioning
    Study

    mousen: not reported in source

    ICR mice
    Comparator
    Social conditioning (SC) group
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The SCC group showed lower OT expression compared to the SC group
    1 context sentence
    Summary · context
    Here, we investigated the conditioned place preference (CPP) in social (conspecific) vs cocaine conditioning, and the expression of central c-Fos, hypothalamic oxytocin (OT) and vasopressin (AVP) in ICR mice.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In ICR mice, oxytocin expression in the paraventricular nucleus was higher after concurrent social versus cocaine conditioning than after cocaine conditioning alone.

    In plain wordsIn mice, the body's own oxytocin in one brain area was higher with combined conditioning than with cocaine conditioning alone.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin expression in the paraventricular nucleus, social versus cocaine conditioning compared with cocaine conditioning
    Study

    mousen: not reported in source

    ICR mice
    Comparator
    Cocaine conditioning (CC) group
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    higher OT and AVP expression in the PVN compared to the CC group.
    1 context sentence
    Summary · context
    Here, we investigated the conditioned place preference (CPP) in social (conspecific) vs cocaine conditioning, and the expression of central c-Fos, hypothalamic oxytocin (OT) and vasopressin (AVP) in ICR mice.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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