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Study · Not a test of the peptide alone · 2016

3 results

Depression-like behaviors in tree shrews and comparison of the effects of treatment with fluoxetine and carbetocin.

Meng X, Shen F, Li C, Li Y, Wang X

Pharmacology, biochemistry, and behavior15 Mar 2016Cited by 16 (Europe PMC)

PMID26987370 (opens in a new tab)DOI10.1016/j.pbb.2016.03.006 (opens in a new tab)PepBankPUB-26987370
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In tree shrews with depression-like behaviours, the oxytocin analog carbetocin was also effective in reversing learned helplessness, in a comparison with fluoxetine.

    In plain wordsIn tree shrews, the oxytocin-like drug carbetocin was also effective in reversing learned helplessness, in a comparison with fluoxetine.

    Peptide
    Oxytocin
    Outcome
    DecreaseLearned helplessness
    Study

    tree shrewn: not reported in source

    Depression-like behaviours induced by multiple unpredictable stimuli
    Comparator
    Fluoxetine
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    compared with fluoxetine, carbetocin was also effective in reversing learned helplessness
    1 context sentence
    Summary · context
    More importantly, we compared the antidepressant effects of fluoxetine and carbetocin, a long-acting oxytocin analog, on specific depression-like behaviors.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In tree shrews with depression-like behaviours, the oxytocin analog carbetocin was also effective in elevating sucrose preference, in a comparison with fluoxetine.

    In plain wordsIn tree shrews, the oxytocin-like drug carbetocin was also effective in raising sucrose preference, in a comparison with fluoxetine.

    Peptide
    Oxytocin
    Outcome
    IncreaseSucrose preference
    Study

    tree shrewn: not reported in source

    Depression-like behaviours induced by multiple unpredictable stimuli
    Comparator
    Fluoxetine
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    compared with fluoxetine, carbetocin was also effective in reversing learned helplessness, elevating sucrose preference
    1 context sentence
    Summary · context
    More importantly, we compared the antidepressant effects of fluoxetine and carbetocin, a long-acting oxytocin analog, on specific depression-like behaviors.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In tree shrews with depression-like behaviours, the oxytocin analog carbetocin was also effective in improving social interaction behaviours, in a comparison with fluoxetine.

    In plain wordsIn tree shrews, the oxytocin-like drug carbetocin was also effective in improving social interaction, in a comparison with fluoxetine.

    Peptide
    Oxytocin
    Outcome
    IncreaseSocial interaction behaviour
    Study

    tree shrewn: not reported in source

    Depression-like behaviours induced by multiple unpredictable stimuli
    Comparator
    Fluoxetine
    Outcome group
    Social behavior and cognition · Mental health and mood

    Source sentences

    Summary
    Our present data displayed that, compared with fluoxetine, carbetocin was also effective in reversing learned helplessness, elevating sucrose preference and improving social interaction behaviors in depression-like animals.
    1 context sentence
    Summary · context
    More importantly, we compared the antidepressant effects of fluoxetine and carbetocin, a long-acting oxytocin analog, on specific depression-like behaviors.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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