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Study · Animal study (in vivo) · mouse · 2015

2 results

[STUDYING THE ROLE OF BRAIN MELANOCORTIN RECEPTORS IN THE SUPPRESSING OF FOOD INTAKE UNDER ETHER STRESS IN MICE].

Bazhan NM, Kulikova EV, Makarova EN, Yakovleva TV, Kazantseva AY

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova1 Dec 2015

PMID26987226 (opens in a new tab)PepBankPUB-26987226
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice under ether stress, central melanocortin receptor stimulation with Melanotan II enhanced stress-induced anorexia.

    In plain wordsIn mice under stress, Melanotan II given into the brain reduced food intake more than stress alone.

    Peptide
    Melanotan II
    Outcome
    DecreaseFood intake under ether stress
    Study

    mousen: not reported in source

    Comparator
    Saline
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (mouse).

    Source sentences

    Summary
    Pharmacological stimulation of the MC receptors enhanced ether stress-induced anorexia and hypercortisolism.
    1 context sentence
    Summary · context
    C57B1/6J male mice were subjected to ether stress (0.5 minute ether anesthesia) before the administration of saline solution or synthetic non-selective blocker (SHU9119) or agonist (Melanotan II) of MC receptors into the lateral brain ventricle.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mice under ether stress, central melanocortin receptor stimulation with Melanotan II enhanced stress-induced hypercortisolism.

    In plain wordsIn mice under stress, Melanotan II given into the brain raised the stress hormone response more than stress alone.

    Peptide
    Melanotan II
    Outcome
    IncreaseStress-induced hypercortisolism (plasma corticosterone)
    Study

    mousen: not reported in source

    Comparator
    Saline
    Outcome group
    Endogenous peptide levels · Endocrine and hormones
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (mouse).

    Source sentences

    Summary
    Pharmacological stimulation of the MC receptors enhanced ether stress-induced anorexia and hypercortisolism.
    1 context sentence
    Summary · context
    C57B1/6J male mice were subjected to ether stress (0.5 minute ether anesthesia) before the administration of saline solution or synthetic non-selective blocker (SHU9119) or agonist (Melanotan II) of MC receptors into the lateral brain ventricle.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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