In Holstein steers, the GHS-R1a antagonist [D-Lys]-GHRP‑6 did not block the insulin changes induced by neuromedin C.
In plain wordsIn steers, a ghrelin-receptor blocker did not stop the rise in insulin caused by neuromedin C.
- Peptide
- GHRP-6
- Outcome
- No significant changeNeuromedin C-induced insulin change with GHS-R1a antagonist
- Study
Holstein steern = 8
- Comparator
- Neuromedin C alone
- Outcome group
- Receptor activity and mechanism · Endocrine and hormones
Source sentences
The NMC-induced changes of insulin and glucose were completely blocked by N-GRP-EE
2 context sentences(design, population, supporting numbers)
but [D-Lys]-GHRP-6 did not block any of these changes.
Eight Holstein steers were randomly and intravenously injected with synthetic bovine gastrin-releasing peptide (GRP; 0.9 nmol/kg BW), neuromedin B (NMB; 0.9 nmol/kg BW), or neuromedin C (NMC; 0.9 nmol/kg BW)
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.