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Study · Other design · mouse · 2016

1 result

Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation.

Fritzen AM, Madsen AB, Kleinert M, Treebak JT, Lundsgaard AM, Jensen TE, Richter EA, Wojtaszewski J, Kiens B, Frøsig C

The Journal of physiology15 Jan 2016Cited by 87 (Europe PMC)

PMID26614120 (opens in a new tab)DOI10.1113/jp271405 (opens in a new tab)PepBankPUB-26614120
Publisher pagePubMedAsk about this study
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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalOther designMechanism

    In mouse muscle, AMPK activation with AICAR did not affect the LC3-II/LC3-I ratio.

    In plain wordsIn mouse muscle, AICAR did not change the LC3-II/LC3-I ratio.

    Peptide
    AICAR (acadesine)
    Outcome
    No significant changeLC3-II/LC3-I ratio
    Study

    mousen: not reported in source

    mouse muscle
    Outcome group
    Receptor activity and mechanism · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Consistently, pharmacological AMPK activation with 5-aminoimidazole-4-carboxamide riboside (AICAR) in mouse muscle did not affect the LC3-II/LC3-I ratio.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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