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Study · Animal study (in vivo) · rat · 2015

2 results

Effects of Geroprotectors on Age-Related Changes in Proteolytic Digestive Enzyme Activities at Different Lighting Conditions.

Morozov AV, Khizhkin EA, Svechkina EB, Vinogradova IA, Ilyukha VA, Anisimov VN, Khavinson VKh

Bulletin of experimental biology and medicine31 Oct 2015Cited by 2 (Europe PMC)

PMID26519279 (opens in a new tab)DOI10.1007/s10517-015-3069-4 (opens in a new tab)PepBankPUB-26519279
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats kept under constant lighting, administration of melatonin and epithalon restored the age dynamics of pepsin activity.

    In plain wordsIn rats kept under constant light, melatonin and epithalon restored the usual age pattern of pepsin activity; effects were not reported separately.

    Peptide
    Epitalon
    Outcome
    Direction not reportedAge dynamics of pepsin activity
    Study

    ratn: not reported in source

    Constant lighting (age-related changes)
    Outcome group
    Aging markers · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of melatonin and epithalon to animals exposed to constant lighting restored age dynamics of pepsin activity and little affected total proteolytic activity.
    1 context sentence
    Summary · context
    We studied the effect of melatonin and epithalon on age-related changes in proteolytic digestive enzyme activity in the pancreas and gastric mucosa of rats kept under different lighting conditions.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats kept under constant lighting, administration of melatonin and epithalon little affected total proteolytic activity.

    In plain wordsIn rats kept under constant light, melatonin and epithalon changed total protein-digesting activity only a little; effects were not reported separately.

    Peptide
    Epitalon
    Outcome
    No significant changeTotal proteolytic activity
    Study

    ratn: not reported in source

    Constant lighting (age-related changes)
    Outcome group
    Aging markers · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of melatonin and epithalon to animals exposed to constant lighting restored age dynamics of pepsin activity and little affected total proteolytic activity.
    1 context sentence
    Summary · context
    We studied the effect of melatonin and epithalon on age-related changes in proteolytic digestive enzyme activity in the pancreas and gastric mucosa of rats kept under different lighting conditions.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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