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Study · Non-randomized trial · n = 32 · 2015

10 results

[EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].

Meshchaninov VN, Tkachenko EL, Zharkov SV, Gavrilov IV, Katyreva IuE

Advances in gerontology = Uspekhi gerontologii1 Jan 2015Cited by 1 (Europe PMC)

PMID26390612 (opens in a new tab)PepBankPUB-26390612
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with polymorbidity, Pinealon showed a less visible geroprophylactic effect than Vesugen.

    In plain wordsIn patients with several illnesses, Pinealon showed a less visible effect on aging than Vesugen.

    Peptide
    Pinealon
    Outcome
    DecreaseGeroprophylactic effect
    Study

    n = 32

    Comparator
    Vesugen
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Vesugen has demonstrated more visible geroprophylactic effect than Pinealon.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.
  2. 02HumanNon-randomized trialEfficacy outcome

    In patients with polymorbidity and organic brain syndrome in remission, Vesugen had a significant anabolic effect, as did Pinealon.

    In plain wordsIn patients with several diseases and organic brain syndrome in remission, Vesugen increased anabolic activity.

    Peptide
    Vesugen (KED)
    Outcome
    IncreaseAnabolic effect
    Study

    n: not reported in source

    Outcome group
    Aging markers · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The preparations of "Pinealon" and "Vesugen" have had the significant anabolic effect.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.
  3. 03HumanNon-randomized trialEfficacy outcome

    In patients with polymorbidity and organic brain syndrome in remission, Vesugen showed a more visible geroprophylactic effect than Pinealon.

    In plain wordsIn these patients, Vesugen showed a greater reported effect against aging than Pinealon.

    Peptide
    Vesugen (KED)
    Outcome
    IncreaseGeroprophylactic effect versus Pinealon
    Study

    n: not reported in source

    Comparator
    Pinealon
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Vesugen has demonstrated more visible geroprophylactic effect than Pinealon.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.
  4. 04HumanNon-randomized trialSafety outcome

    In patients with polymorbidity and organic brain syndrome in remission, Vesugen and Pinealon did not affect chromatin condensation.

    In plain wordsIn patients with several diseases and organic brain syndrome in remission, Vesugen did not change chromatin condensation.

    Peptide
    Vesugen (KED)
    Outcome
    No significant changeChromatin condensation
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Pinealon and Vesugen haven't affected the degree of chromatin condensation, so they are safe on nuclear genetic level.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

Studies that did not test the peptide alone6

In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Pinealon.

  1. 05HumanNot a test of Pinealon aloneNon-randomized trialEfficacy outcome

    In patients with polymorbidity and organic brain syndrome, Pinealon and Vesugen preparations showed a significant anabolic effect without separate peptide estimates.

    In plain wordsIn patients with several illnesses, Pinealon and Vesugen preparations showed an anabolic effect without separate results for each peptide.

    Peptide
    Pinealon
    Outcome
    IncreaseAnabolic effect
    Study

    n = 32

    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    The preparations of "Pinealon" and "Vesugen" have had the significant anabolic effect.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

  2. 06HumanNot a test of Pinealon aloneNon-randomized trialEfficacy outcome

    In patients with polymorbidity and organic brain syndrome, Pinealon and Vesugen preparations improved the activity of the central nervous system and other vital organs without separate peptide estimates.

    In plain wordsIn patients with several illnesses, Pinealon and Vesugen preparations improved nervous system and other organ activity without separate results for each peptide.

    Peptide
    Pinealon
    Outcome
    IncreaseActivity of the central nervous system and other vital organs
    Study

    n = 32

    Outcome group
    Overall treatment effect · Whole body

    Source sentences

    Summary
    They have improved the activity of the Central nervous system and other vital organs, which slows the rate of aging by biological age indicators.
    3 context sentences
    Summary · context
    The preparations of "Pinealon" and "Vesugen" have had the significant anabolic effect.
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

  3. 07HumanNot a test of Pinealon aloneNon-randomized trialActivity measurement

    In patients with polymorbidity, the study of Pinealon and Vesugen found prooxidant activity through chemiluminescence without separate peptide estimates.

    In plain wordsIn patients with several illnesses, the Pinealon and Vesugen study found prooxidant activity without separate results for each peptide.

    Peptide
    Pinealon
    Outcome
    IncreaseProoxidant activity
    Study

    n = 32

    Outcome group
    Oxidative stress · Whole body

    Source sentences

    Summary
    At the same time we've found the prooxidant activity through chemiluminescence.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

  4. 08HumanNot a test of Pinealon aloneNon-randomized trialSafety outcome

    In patients with polymorbidity, the Pinealon and Vesugen study reported decreased blood CD34+ cell markers, interpreted as significant inhibition of hemopoiesis.

    In plain wordsIn patients with several illnesses, the Pinealon and Vesugen study found fewer blood cell markers and interpreted this as reduced blood formation.

    Peptide
    Pinealon
    Outcome
    DecreaseCD34+ hematopoietic cell markers
    Study

    n = 32

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Decrease of markers CD34+ positive hematopoietic polypotent cells in blood has shown significant inhibition of hemopoiesis.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

  5. 09HumanNot a test of Pinealon aloneNon-randomized trialSafety outcome

    In patients with polymorbidity and organic brain syndrome, Pinealon and Vesugen did not affect the degree of chromatin condensation, without separate peptide estimates.

    In plain wordsIn patients with several illnesses, Pinealon and Vesugen did not change chromatin condensation, with no separate results for each peptide.

    Peptide
    Pinealon
    Outcome
    No significant changeChromatin condensation
    Study

    n = 32

    Outcome group
    Adverse events · Whole body

    Source sentences

    Summary
    Pinealon and Vesugen haven't affected the degree of chromatin condensation, so they are safe on nuclear genetic level.
    2 context sentences
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

  6. 10HumanNot a test of Pinealon aloneNon-randomized trialEfficacy outcome

    In patients with polymorbidity, Pinealon and Vesugen preparations slowed aging by biological age indicators without separate peptide estimates.

    In plain wordsIn patients with several illnesses, Pinealon and Vesugen preparations slowed aging according to biological age indicators without separate peptide results.

    Peptide
    Pinealon
    Outcome
    DecreaseRate of aging by biological age indicators
    Study

    n = 32

    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    They have improved the activity of the Central nervous system and other vital organs, which slows the rate of aging by biological age indicators.
    3 context sentences
    Summary · context
    The preparations of "Pinealon" and "Vesugen" have had the significant anabolic effect.
    Summary · context
    We've estimated the cellular and metabolic part of geroprophylactic effects of short synthetic tripeptides vesugen and pinealon for correction of the biological age.
    Summary · context
    32 people (18 men, 12 women) aged 41-83 years with polymorbidity and the organic brain syndrome in remission participated in the study.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 16:35 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    14 Oct 2026, 05:02 UTC

    Study results updated

  3. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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