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Study · Randomized controlled trial · 2015

10 results

[Effect of Acupuncture on Prognosis and Immune Function of Sepsis Patients].

Xiao QS, Ma MY, Zhang XS, Deng MH, Yang Yan Z

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine1 Jul 2015Cited by 7 (Europe PMC)

PMID26380438 (opens in a new tab)PepBankPUB-26380438
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

10 results from studies that gave the peptide. 10 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care raised CD3+ T cells more than routine care alone.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care raised CD3+ T cells more than routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseCD3+ T cell increase
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care raised CD4+ T cells more than routine care alone.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care raised CD4+ T cells more than routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseCD4+ T cell increase
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care raised CD8+ T cells more than routine care alone.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care raised CD8+ T cells more than routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseCD8+ T cell increase
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care raised IgG more than routine care alone.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care raised IgG antibodies more than routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseIgG increase
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  5. 05HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care raised IgA more than routine care alone.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care raised IgA antibodies more than routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseIgA increase
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  6. 06HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care raised IgM more than routine care alone.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care raised IgM antibodies more than routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseIgM increase
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  7. 07HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care shortened ICU stay compared with the control group.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care shortened ICU stay compared with routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseICU hospitalization length
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Intensive care and hospital outcomes · Whole body
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Compared with the control group, the ICU hospitalization length was significantly shortened, the hospital readmission rate and the 28-day mortality were lower in the thymosin alpha1 group and the acupuncture treatment group (P < 0.05, P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  8. 08HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care lowered the hospital readmission rate compared with the control group.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care lowered readmission to hospital compared with routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseHospital readmission rate
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Intensive care and hospital outcomes · Whole body
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Compared with the control group, the ICU hospitalization length was significantly shortened, the hospital readmission rate and the 28-day mortality were lower in the thymosin alpha1 group and the acupuncture treatment group (P < 0.05, P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  9. 09HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, thymosin alpha‑1 added to routine care lowered 28-day mortality compared with the control group.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 added to routine care lowered 28-day deaths compared with routine care alone.

    Peptide
    Thymosin alpha-1
    Outcome
    Decrease28-day mortality
    Study

    n: not reported in source

    Comparator
    Routine treatment (control)
    Outcome group
    Mortality · Whole body
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    Compared with the control group, the ICU hospitalization length was significantly shortened, the hospital readmission rate and the 28-day mortality were lower in the thymosin alpha1 group and the acupuncture treatment group (P < 0.05, P < 0.01).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.
  10. 10HumanRandomized controlled trialEfficacy outcome

    In patients with sepsis, no significant difference in each index was found between the thymosin alpha‑1 group and the acupuncture group.

    In plain wordsIn patients with sepsis, thymosin alpha‑1 and acupuncture groups did not differ on the measured indices.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeImmune indices and prognosis, thymosin alpha 1 versus acupuncture
    Study

    n: not reported in source

    Comparator
    Acupuncture
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1.6 mg once per day · subdermal injection · 6 daysAs given in this study (human).

    Source sentences

    Summary
    There was no statistical difference in each index between the thymosin alpha1 group and the acupuncture treatment group (P > 0.05).
    2 context sentences
    Summary · context
    Ninety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group.
    Summary · context
    Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

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Terms as the source lists them.

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