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Study · Not a test of the peptide alone · 2016

3 results

Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy.

Subirós N, Pérez-Saad HM, Berlanga JA, Aldana L, García-Illera G, Gibson CL, García-Del-Barco D

Neurological research1 Mar 2016Cited by 8 (Europe PMC)

PMID26311576 (opens in a new tab)DOI10.1179/1743132815y.0000000089 (opens in a new tab)PepBankPUB-26311576
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In gerbils with brain ischaemia, rhEGF plus GHRP‑6 given up to 4 hours after injury improved survival versus vehicle.

    In plain wordsIn gerbils with brain ischaemia, rhEGF plus GHRP‑6 improved survival compared with vehicle.

    Peptide
    GHRP-6
    Outcome
    IncreaseSurvival
    Study

    Mongolian gerbiln: not reported in source

    global brain ischaemia
    Comparator
    vehicle treatment
    Outcome group
    Mortality · Whole body

    Source sentences

    Summary
    The coadministration of rhEGF and GHRP-6 at doses of 100 and 600 μg/kg, respectively, administered up to 4 hours following the ischaemic insult, significantly improved survival and neurological outcome, and reduced infarct volume compared with vehicle treatment.
    1 context sentence
    Summary · context
    Mongolian gerbils underwent 15 minutes occlusion of both common carotid arteries.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In gerbils with brain ischaemia, rhEGF plus GHRP‑6 given up to 4 hours after injury improved neurological outcome versus vehicle.

    In plain wordsIn gerbils with brain ischaemia, rhEGF plus GHRP‑6 improved neurological outcome compared with vehicle.

    Peptide
    GHRP-6
    Outcome
    IncreaseNeurological outcome
    Study

    Mongolian gerbiln: not reported in source

    global brain ischaemia
    Comparator
    vehicle treatment
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    The coadministration of rhEGF and GHRP-6 at doses of 100 and 600 μg/kg, respectively, administered up to 4 hours following the ischaemic insult, significantly improved survival and neurological outcome, and reduced infarct volume compared with vehicle treatment.
    1 context sentence
    Summary · context
    Mongolian gerbils underwent 15 minutes occlusion of both common carotid arteries.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In gerbils with brain ischaemia, rhEGF plus GHRP‑6 given up to 4 hours after injury reduced infarct volume versus vehicle.

    In plain wordsIn gerbils with brain ischaemia, rhEGF plus GHRP‑6 reduced infarct volume compared with vehicle.

    Peptide
    GHRP-6
    Outcome
    DecreaseInfarct volume
    Study

    Mongolian gerbiln: not reported in source

    global brain ischaemia
    Comparator
    vehicle treatment
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    The coadministration of rhEGF and GHRP-6 at doses of 100 and 600 μg/kg, respectively, administered up to 4 hours following the ischaemic insult, significantly improved survival and neurological outcome, and reduced infarct volume compared with vehicle treatment.
    1 context sentence
    Summary · context
    Mongolian gerbils underwent 15 minutes occlusion of both common carotid arteries.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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