In ovariectomized rats, β-TCP plus teriparatide produced significantly better bone healing in the quantity and quality of new bone.
In plain wordsIn ovariectomized rats, β-TCP plus teriparatide improved the quantity and quality of new bone.
- Peptide
- Teriparatide (PTH 1-34)
- Outcome
- IncreaseBone healing quantity and quality
- Study
ratn: not reported in source
ovariectomized rat femoral metaphysis defect- Outcome group
- Bone and joint · Musculoskeletal
Source sentences
When the β-TCP and PTH were used, histological, biochemistry and histomor-phometric evaluations revealed significantly better bone healing in terms of quantity and quality of the newly formed bone.
1 context sentence(design, population, supporting numbers)
A critical size defect of 3mm in diameter, a through-hole bone defect, was drilled into each distal femur of the ovariectomised rats. The hole was filled with β-TCP and the rat was injected PTH Teriparatide (30μg/kg) in peritoneum 5 times per week. After 4and 8 weeks the animals were killed and the…
In this study, Teriparatide (PTH 1-34) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Teriparatide (PTH 1-34).