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Study · Measured the body's own peptide · 2015

1 result

Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone.

Bosch OG, Eisenegger C, Gertsch J, von Rotz R, Dornbierer D, Gachet MS, Heinrichs M, Wetter TC, Seifritz E, Quednow BB

Psychoneuroendocrinology17 Jul 2015Cited by 26 (Europe PMC)

PMID26209926 (opens in a new tab)DOI10.1016/j.psyneuen.2015.07.167 (opens in a new tab)PepBankPUB-26209926
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In healthy men, gamma-hydroxybutyrate (20mg/kg) did not change plasma oxytocin levels compared with placebo.

    In plain wordsIn healthy men, GHB did not change the body's own oxytocin levels in blood compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin level after GHB
    Study

    n = 16

    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    oxytocin and testosterone, cortisol, aldosterone, DHEA, and ACTH levels remained unaffected.
    2 context sentences
    Summary · context
    GHB has mood-enhancing and prosocial effects without affecting social hormones such as oxytocin and testosterone.
    Summary · context
    GHB (20mg/kg) was tested in 16 healthy males, using a randomized, placebo-controlled, cross-over design.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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