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Study · Randomized controlled trial · n = 97 · 2015

3 results

Effects of intranasal oxytocin on steroid hormones in men and women.

Wirth MM, Gaffey AE, Martinez BS

Neuropsychobiology2 Jun 2015Cited by 15 (Europe PMC)

PMID26044829 (opens in a new tab)DOI10.1159/000381023 (opens in a new tab)PepBankPUB-26044829
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy women and men, intranasal oxytocin 24 IU did not change salivary testosterone compared with saline placebo.

    In plain wordsIn healthy women and men, oxytocin did not change saliva testosterone compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeSalivary testosterone
    Study

    n = 97

    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin had no effects on testosterone, progesterone, or cortisol in women or men.
    1 context sentence
    Summary · context
    In randomized, double-blind experiments, we administered oxytocin (24 IU) or saline placebo to 97 healthy participants.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy women and men, intranasal oxytocin 24 IU did not change salivary progesterone compared with saline placebo.

    In plain wordsIn healthy women and men, oxytocin did not change saliva progesterone compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeSalivary progesterone
    Study

    n = 97

    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin had no effects on testosterone, progesterone, or cortisol in women or men.
    1 context sentence
    Summary · context
    In randomized, double-blind experiments, we administered oxytocin (24 IU) or saline placebo to 97 healthy participants.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy women and men, intranasal oxytocin 24 IU did not change salivary cortisol compared with saline placebo.

    In plain wordsIn healthy women and men, oxytocin did not change saliva cortisol compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeSalivary cortisol
    Study

    n = 97

    Comparator
    Placebo
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin had no effects on testosterone, progesterone, or cortisol in women or men.
    1 context sentence
    Summary · context
    In randomized, double-blind experiments, we administered oxytocin (24 IU) or saline placebo to 97 healthy participants.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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