In male participants, neuroticism did not modulate the effect of intranasal oxytocin on the neural response to positive or negative social interactions.
In plain wordsIn men, personality (neuroticism) did not change how oxytocin affected brain responses to positive or negative social interactions, compared with placebo.
- Peptide
- Oxytocin
- Outcome
- No significant changeNeuroticism moderation of oxytocin effect on neural response to social interactions
- Study
n: not reported in source
- Comparator
- Placebo
- Outcome group
- Brain and neuronal activity · Nervous system and cognition
- Studied dose
- 24 IU · intranasalAs given in this study (human).
Source sentences
Neuroticism did not modulate the effect of intranasal OT treatment on the neural response to either positive or negative social interactions.
1 context sentence(design, population, supporting numbers)
In a double-blind, placebo-controlled study, 153 male participants were randomized to receive 24 IU intranasal OT, 20 IU AVP or placebo.