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Study · Animal study (in vivo) · rat · 2014

3 results

[Influence of delta-sleep peptide on the enzymes activity of mitochondrial electron transport chain in various rat tissues during aging of the organism].

Bondarenko TI, Kutilin DS, Mikhaleva II

Advances in gerontology = Uspekhi gerontologii1 Jan 2014

PMID25826998 (opens in a new tab)DOI10.1134/s2079057015010038 (opens in a new tab)PepBankPUB-25826998
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats aged 2-24 months, subcutaneous DSIP had a stabilizing effect on NADH-dehydrogenase activity in mitochondrial fractions of various tissues.

    In plain wordsIn rats, DSIP injections stabilized the activity of a mitochondrial enzyme, NADH-dehydrogenase, in several tissues.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableNADH-dehydrogenase activity in mitochondrial fractions
    Study

    ratn: not reported in source

    physiological aging, rats aged 2-24 months
    Outcome group
    Mitochondrial function · Aging and longevity
    Studied dose
    100 μg/kg body weight · subcutaneous · courses of 5 consecutive days per monthAs given in this study (rat).

    Source sentences

    Summary
    has a stabilizing effect on the NADH-dehydrogenase activity in the mitochondrial fractions of various tissues
    1 context sentence
    Summary · context
    subcutaneous injection of exogenous delta-sleep inducing peptide (DSIP) to rats aged 2-24 months in a dose of 100 μg/kg animal body weight by courses of 5 consecutive days per month
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats aged 2-24 months, subcutaneous DSIP did not change the activity of succinate dehydrogenase.

    In plain wordsIn rats, DSIP injections did not change the activity of the mitochondrial enzyme succinate dehydrogenase.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeSuccinate dehydrogenase activity
    Study

    ratn: not reported in source

    physiological aging, rats aged 2-24 months
    Outcome group
    Mitochondrial function · Aging and longevity
    Studied dose
    100 μg/kg body weight · subcutaneous · courses of 5 consecutive days per monthAs given in this study (rat).

    Source sentences

    Summary
    herewith the activity of succinate dehydrogenase did not change
    1 context sentence
    Summary · context
    subcutaneous injection of exogenous delta-sleep inducing peptide (DSIP) to rats aged 2-24 months in a dose of 100 μg/kg animal body weight by courses of 5 consecutive days per month
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats aged 2-24 months, subcutaneous DSIP was accompanied by increasing capacity of the antioxidant system.

    In plain wordsIn rats, DSIP injections were accompanied by a higher capacity of the antioxidant system.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseAntioxidant system capacity
    Study

    ratn: not reported in source

    physiological aging, rats aged 2-24 months
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    100 μg/kg body weight · subcutaneous · courses of 5 consecutive days per monthAs given in this study (rat).

    Source sentences

    Summary
    together with increasing capacity of the antioxidant system
    1 context sentence
    Summary · context
    subcutaneous injection of exogenous delta-sleep inducing peptide (DSIP) to rats aged 2-24 months in a dose of 100 μg/kg animal body weight by courses of 5 consecutive days per month

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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