Skip to content

Study · Animal study (in vivo) · rat · 2014

2 results

[Influence of delta-sleep inducing peptide on the state of lysosomal membranes and intensity of lysosomal proteolysis in different rat tissues during physiological aging of the organism].

Kutilin DS, Bondarenko TI, Mikhaleva II

Advances in gerontology = Uspekhi gerontologii1 Jan 2014Cited by 3 (Europe PMC)

PMID25826997 (opens in a new tab)DOI10.1134/s2079057015010063 (opens in a new tab)PepBankPUB-25826997
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats aged 2-24 months, subcutaneous DSIP had a stabilizing effect on the state of lysosomal membranes in brain, heart muscle and liver.

    In plain wordsIn rats, DSIP injections stabilized the membranes of lysosomes in brain, heart and liver tissue.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableLysosomal membrane state
    Study

    ratn: not reported in source

    physiological aging, rats aged 2-24 months
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    100 μg/kg body weight · subcutaneous · courses of 5 consecutive days per monthAs given in this study (rat).

    Source sentences

    Summary
    has a stabilizing effect on the state of lysosomal membranes in rat tissues (brain, heart muscle and liver) at different ontogenetic stages
    1 context sentence
    Summary · context
    subcutaneous injection of exogenous delta-sleep inducing peptide (DSIP) to rats aged 2-24 months in a dose of 100 μg/kg animal body weight by courses of 5 consecutive days per month
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats aged 2-24 months, subcutaneous DSIP was accompanied by increased intensity of lysosomal proteolysis in brain, heart muscle and liver.

    In plain wordsIn rats, DSIP injections were accompanied by more lysosomal protein breakdown in brain, heart and liver tissue.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseLysosomal proteolysis intensity
    Study

    ratn: not reported in source

    physiological aging, rats aged 2-24 months
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    100 μg/kg body weight · subcutaneous · courses of 5 consecutive days per monthAs given in this study (rat).

    Source sentences

    Summary
    this effect is accompanied by increasing intensity of lysosomal proteolysis in these tissues
    1 context sentence
    Summary · context
    subcutaneous injection of exogenous delta-sleep inducing peptide (DSIP) to rats aged 2-24 months in a dose of 100 μg/kg animal body weight by courses of 5 consecutive days per month

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.