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Study · Measured the body's own peptide · 2015

1 result

Differential impact of stress on hypothalamic-pituitary-adrenal axis: gene expression changes in Lewis and Fisher rats.

Ergang P, Vodička M, Soták M, Klusoňová P, Behuliak M, Řeháková L, Zach P, Pácha J

Psychoneuroendocrinology27 Dec 2014Cited by 21 (Europe PMC)

PMID25591115 (opens in a new tab)DOI10.1016/j.psyneuen.2014.12.013 (opens in a new tab)PepBankPUB-25591115
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelOther designOther

    In Lewis and Fisher 344 rats, variable stress stimulated the expression of paraventricular oxytocin (OXT) in both strains.

    In plain wordsIn rats, stress raised the body's own oxytocin gene activity in a brain region in both strains.

    Peptide
    Oxytocin
    Outcome
    IncreaseParaventricular OXT expression after variable stress
    Study

    ratn: not reported in source

    Lewis and Fisher 344 rats
    Outcome group
    Anxiety and mood · Endocrine and hormones

    Source sentences

    Summary
    Stress also stimulated the expression of paraventricular OXT, CRH, UCN3 and PACAP in both strains
    1 context sentence
    Summary · context
    The aim of the present work was to study the influence of variable stress on the expression of 11β-hydroxysteroid dehydrogenase type 1 (11HSD1) and the neuropeptides corticotropin-releasing hormone (CRH), urocortins 2 and 3(UCN2, UCN3), arginine vasopressin (AVP), oxytocin (OXT) and adenylate cyclas…

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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