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Study · Animal study (in vivo) · rat · 2013

4 results

[Opposite Semax influence on conditioning and functional disturbances of avoidance responses in rats].

Inozemtsev AN, Agapitova AE, Bokieva SB, Glazova NIu, Levitskaia NG, Kamenskiĭ AA, Miasoedov NF

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova1 Nov 2013

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats trained to avoid foot-shock by jumping on a shelf, intraperitoneal Semax at 0.05 mg/kg accelerated acquisition of one-way active avoidance.

    In plain wordsIn rats, Semax at 0.05 mg/kg given by injection into the abdomen sped up learning to avoid a foot-shock.

    Peptide
    Semax
    Outcome
    IncreaseAcquisition of one-way active avoidance response
    Study

    ratn: not reported in source

    Active avoidance training (foot-shock)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.05 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    It was shown that intraperitoneal Semax administration at a dose of 0.05 mg/kg accelerated acquisition of one-way active avoidance response when rats were trained to avoid electric foot-shock by jumping on the shelf.
    1 context sentence
    Summary · context
    Semax effects on formation of active avoidance reaction in rats in different experimental models have been studied.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats trained in a shuttle-box, Semax increased the electroshock threshold that provoked movement in the box.

    In plain wordsIn rats in a shuttle-box, Semax raised the electric shock level needed to make the rats move.

    Peptide
    Semax
    Outcome
    IncreaseElectroshock threshold in shuttle-box
    Study

    ratn: not reported in source

    Active avoidance training (foot-shock)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    the peptide increased the electroshock threshold value required to provocation of rat moving in experimental box
    1 context sentence
    Summary · context
    Semax effects on formation of active avoidance reaction in rats in different experimental models have been studied.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats trained in a shuttle-box, Semax delayed acquisition of two-way active avoidance.

    In plain wordsIn rats in a shuttle-box, Semax slowed learning of a two-way avoidance task.

    Peptide
    Semax
    Outcome
    DecreaseAcquisition of two-way active avoidance response in shuttle-box
    Study

    ratn: not reported in source

    Active avoidance training (foot-shock)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    delayed acquisition of two-way active avoidance response.
    1 context sentence
    Summary · context
    Semax effects on formation of active avoidance reaction in rats in different experimental models have been studied.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats in a shuttle-box, Semax stimulated restoration of the avoidance response after functional disturbances caused by acute change of the environment.

    In plain wordsIn rats, Semax helped the avoidance response to recover after the test setting was changed.

    Peptide
    Semax
    Outcome
    IncreaseRestoration of avoidance response after functional disturbance
    Study

    ratn: not reported in source

    Active avoidance training (foot-shock)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At the same time Semax stimulated avoidance response restoration in shuttle-box after functional disturbances induced by acute modification of cause-effect and spatial relationships in experimental environment.
    1 context sentence
    Summary · context
    Semax effects on formation of active avoidance reaction in rats in different experimental models have been studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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