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Study · In vitro (cells) · 2015

1 result

β-Amyloid peptides display protective activity against the human Alzheimer's disease-associated herpes simplex virus-1.

Bourgade K, Garneau H, Giroux G, Le Page AY, Bocti C, Dupuis G, Frost EH, Fülöp T Jr

Biogerontology7 Nov 2014Cited by 177 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In cell lines, antimicrobial peptide LL‑37 prevented HSV-1 infection independently of its sequence of addition relative to the virus.

    In plain wordsIn cells, LL‑37 prevented herpes simplex virus 1 infection whether it was added before or after the virus.

    Peptide
    LL-37
    Outcome
    DecreasePrevention of HSV-1 infection
    Study

    n: not reported in source

    Fibroblast, epithelial and neuronal cell lines challenged with HSV-1
    Outcome group
    Antiviral activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In comparison, antimicrobial peptide LL-37 prevented HSV-1 infection independently of its sequence of addition.
    1 context sentence
    Summary · context
    Here, fibroblast, epithelial and neuronal cell lines were exposed to Aβ 1-40 or Aβ 1-42 and challenged with HSV-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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