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Study · Not a test of the peptide alone · 2014

7 results

[Possibilities of the pharmacological correction of adaptive reactions of human organism in short-term moving from middle to high altitude].

Kundashev UK, Zurdinov AZ, Barchukov VG

Eksperimental'naia i klinicheskaia farmakologiia1 Jan 2014

PMID25365868 (opens in a new tab)PepBankPUB-25365868
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Bromantane.

  1. 01HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, metaprote plus ladasten improved tolerance of physical activity.

    In plain wordsIn volunteers at high altitude, metaprote plus ladasten improved physical activity tolerance.

    Peptide
    Bromantane
    Outcome
    IncreasePhysical activity tolerance at altitude
    Study

    n: not reported in source

    Outcome group
    Exercise and physical function · Whole body

    Source sentences

    Summary
    It is established that a combination of metaprote and ladasten (in doses of 0.125 and 0.1 g, respectively) favors acceleration of the short-term adaptation, which is manifested by the improved tolerance of physical activity at high altitude and the acceleration of white and red blood growth.
    2 context sentences
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

  2. 02HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, metaprote plus ladasten accelerated white blood growth.

    In plain wordsIn volunteers at high altitude, metaprote plus ladasten accelerated white blood growth.

    Peptide
    Bromantane
    Outcome
    IncreaseWhite blood growth
    Study

    n: not reported in source

    Outcome group
    Immune response · Whole body

    Source sentences

    Summary
    It is established that a combination of metaprote and ladasten (in doses of 0.125 and 0.1 g, respectively) favors acceleration of the short-term adaptation, which is manifested by the improved tolerance of physical activity at high altitude and the acceleration of white and red blood growth.
    2 context sentences
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

  3. 03HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, metaprote plus ladasten accelerated red blood growth.

    In plain wordsIn volunteers at high altitude, metaprote plus ladasten accelerated red blood growth.

    Peptide
    Bromantane
    Outcome
    IncreaseRed blood growth
    Study

    n: not reported in source

    Outcome group
    Blood counts and hematopoiesis · Whole body

    Source sentences

    Summary
    It is established that a combination of metaprote and ladasten (in doses of 0.125 and 0.1 g, respectively) favors acceleration of the short-term adaptation, which is manifested by the improved tolerance of physical activity at high altitude and the acceleration of white and red blood growth.
    2 context sentences
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

  4. 04HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, metaprote plus ladasten produced more pronounced adaptive tolerance responses than hypoxen alone.

    In plain wordsIn volunteers at high altitude, metaprote plus ladasten improved adaptive tolerance more than hypoxen alone.

    Peptide
    Bromantane
    Outcome
    IncreaseAdaptive tolerance response versus hypoxen
    Study

    n: not reported in source

    Comparator
    hypoxen alone
    Outcome group
    Exercise and physical function · Whole body

    Source sentences

    Summary
    In case of the combined administration of both actoprotectors, the adaptive reactions of tolerance and blood system were more pronounced in comparison to the administration of hypoxen (0.5 g) alone.
    2 context sentences
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

  5. 05HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, metaprote plus ladasten produced more pronounced adaptive blood system responses than hypoxen alone.

    In plain wordsIn volunteers at high altitude, metaprote plus ladasten strengthened blood system adaptation more than hypoxen alone.

    Peptide
    Bromantane
    Outcome
    IncreaseAdaptive blood system response versus hypoxen
    Study

    n: not reported in source

    Comparator
    hypoxen alone
    Outcome group
    Blood counts and hematopoiesis · Whole body

    Source sentences

    Summary
    In case of the combined administration of both actoprotectors, the adaptive reactions of tolerance and blood system were more pronounced in comparison to the administration of hypoxen (0.5 g) alone.
    2 context sentences
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

  6. 06HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, energy supply adaptation occurred earlier with metaprote plus ladasten than with hypoxen.

    In plain wordsIn volunteers at high altitude, energy supply adaptation occurred earlier with metaprote plus ladasten than with hypoxen.

    Peptide
    Bromantane
    Outcome
    Direction not reportedEnergy supply adaptation versus hypoxen
    Study

    n: not reported in source

    Comparator
    hypoxen
    Outcome group
    Exercise and physical function · Whole body

    Source sentences

    Summary
    A distinguishing feature of the reaction of the human organism upon taking the combination of actoprotectors was that adaptation of the energy supply system (judging from metabolites studied) already took place in the first hours of staying at high altitudes, while the adaptation upon taking 0.5 g h…
    2 context sentences
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

  7. 07HumanNot a test of Bromantane aloneNon-randomized trialEfficacy outcome

    In high-altitude volunteers, energy supply adaptation occurred earlier with metaprote plus ladasten than with placebo.

    In plain wordsIn volunteers at high altitude, energy supply adaptation occurred earlier with metaprote plus ladasten than with placebo.

    Peptide
    Bromantane
    Outcome
    Direction not reportedEnergy supply adaptation versus placebo
    Study

    n: not reported in source

    Comparator
    placebo
    Outcome group
    Exercise and physical function · Whole body

    Source sentences

    Summary
    adaptation of the energy supply system (judging from metabolites studied) already took place in the first hours of staying at high altitudes, while the adaptation upon taking 0.5 g hypoxen was observed on the 3rd day and the adaptive reactions in placebo group were still developing on the 3rd day.
    3 context sentences
    Summary · context
    A distinguishing feature of the reaction of the human organism upon taking the combination of actoprotectors was that
    Summary · context
    It was assessed the efficacy of drugs belonging to the class of actoprotectors and antihypoxants, which are prescribed for short-term adaptation of the human organism moving from middle altitude (1670 m) to high altitude (3750 m).
    Summary · context
    Drugs or placebo were administered in tablets after the first testing (one hour before moving to high altitude), upon arrival at altitude (next day, after breakfast), and on the third day (one hour before last testing).

    In this study, Bromantane was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Bromantane.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

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