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Study · Measured the body's own peptide · 2015

4 results

Diagnostic value of anti-microbial peptide, cathelicidin in congenital pneumonia.

Gad GI, Abushady NM, Fathi MS, Elsaadany W

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians27 Nov 2014Cited by 15 (Europe PMC)

PMID25354286 (opens in a new tab)DOI10.3109/14767058.2014.981806 (opens in a new tab)PepBankPUB-25354286
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In neonates, serum cathelicidin (LL‑37) was higher in congenital pneumonia than in healthy controls.

    In plain wordsIn newborns with congenital pneumonia, the body's own cathelicidin (LL‑37) level in blood was higher than in healthy newborns.

    Peptide
    LL-37
    Outcome
    IncreaseSerum cathelicidin in congenital pneumonia versus controls
    Study

    n = 60

    Comparator
    Healthy neonates
    Outcome group
    Infection and antimicrobial activity · Respiratory

    Source sentences

    Summary
    Neonates with congenital pneumonia had significantly higher serum cathelicidin and lower serum 25(OH)D compared to controls.
    2 context sentences
    Summary · context
    The study included 30 neonates with congenital pneumonia and culture proven sepsis admitted to neonatal intensive care unit of Ain Shams University and 30 healthy neonates as control group.
    Summary · context
    All neonates were subjected to history taking, clinical examination and measurement of serum 25(OH)D and cathelicidin.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    A serum cathelicidin cut-off of 17 pg/mmol diagnosed congenital pneumonia with 93% sensitivity and 86% specificity.

    In plain wordsIn newborns, a natural cathelicidin cut-off value picked out congenital pneumonia with 93% sensitivity and 86% specificity.

    Peptide
    LL-37
    Outcome
    Not applicableDiagnostic accuracy of cathelicidin for congenital pneumonia
    Study

    n = 60

    Outcome group
    Infection and antimicrobial activity · Respiratory

    Measurements

    Cut-off
    17 pg/mmol
    cathelicidin
    Sensitivity
    93%
    congenital pneumonia
    Specificity
    86%
    congenital pneumonia

    Source sentences

    Summary
    Cut-off value of cathelicidin to diagnose congenital pneumonia was 17 pg/mmol with 93% sensitivity and 86% specificity.
    2 context sentences
    Summary · context
    The study included 30 neonates with congenital pneumonia and culture proven sepsis admitted to neonatal intensive care unit of Ain Shams University and 30 healthy neonates as control group.
    Summary · context
    All neonates were subjected to history taking, clinical examination and measurement of serum 25(OH)D and cathelicidin.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    Among neonates with congenital pneumonia, serum cathelicidin was negatively correlated with Apgar score at 1 and 5 minutes.

    In plain wordsIn newborns with pneumonia, higher natural cathelicidin levels were linked to lower Apgar scores.

    Peptide
    LL-37
    Outcome
    DecreaseCorrelation of cathelicidin with Apgar score
    Study

    n = 30

    Outcome group
    Infection and antimicrobial activity · Respiratory

    Source sentences

    Summary
    Serum cathelicidin was negatively correlated with Apgar score at 1 and 5 min and positively correlated with length of stay among patient group.
    2 context sentences
    Summary · context
    The study included 30 neonates with congenital pneumonia and culture proven sepsis admitted to neonatal intensive care unit of Ain Shams University and 30 healthy neonates as control group.
    Summary · context
    All neonates were subjected to history taking, clinical examination and measurement of serum 25(OH)D and cathelicidin.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    Among neonates with congenital pneumonia, serum cathelicidin was positively correlated with length of hospital stay.

    In plain wordsIn newborns with pneumonia, higher natural cathelicidin levels were linked to longer hospital stays.

    Peptide
    LL-37
    Outcome
    IncreaseCorrelation of cathelicidin with length of stay
    Study

    n = 30

    Outcome group
    Infection and antimicrobial activity · Respiratory

    Source sentences

    Summary
    Serum cathelicidin was negatively correlated with Apgar score at 1 and 5 min and positively correlated with length of stay among patient group.
    2 context sentences
    Summary · context
    The study included 30 neonates with congenital pneumonia and culture proven sepsis admitted to neonatal intensive care unit of Ain Shams University and 30 healthy neonates as control group.
    Summary · context
    All neonates were subjected to history taking, clinical examination and measurement of serum 25(OH)D and cathelicidin.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

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