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Study · Non-randomized trial · n = 30 · 2014

3 results

[Effect of cerebrolysin on disadaptation syndrome in patients with ischemic stroke].

Iakupov EZ, Ovsiannikova KS

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2014Cited by 1 (Europe PMC)

PMID25345642 (opens in a new tab)PepBankPUB-25345642
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with acute ischemic stroke, cerebrolysin treatment improved HRV spectrum analysis indicators compared with controls.

    In plain wordsIn patients with stroke, cerebrolysin improved heart rate variability spectrum indicators compared with controls.

    Peptide
    Cerebrolysin
    Outcome
    Not applicableHRV spectrum analysis indicators
    Study

    n = 30

    Comparator
    Controls
    Outcome group
    Autonomic function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared to the controls, significant positive changes in the indicators of HRV spectrum analysis and cardiointervalography as well as the reduction in neurological deficit in patients treated with cerebrolysin, which has neurotrophic and neuroprotective properties, was found.
    2 context sentences
    Summary · context
    To study the neurotrophic and neuroprotective effects of cerebrolysin on the autonomic homeostasis in patients with ischemic stroke (IS) using heart rate variability (HRV) method.
    Summary · context
    Thirty patients, 12 men and 18 women (mean age 65.0±7.8 years) in the acute stage of IS were enrolled in the study.
  2. 02HumanNon-randomized trialEfficacy outcome

    In patients with acute ischemic stroke, cerebrolysin treatment improved cardiointervalography indicators compared with controls.

    In plain wordsIn patients with stroke, cerebrolysin improved cardiointervalography indicators compared with controls.

    Peptide
    Cerebrolysin
    Outcome
    Not applicableCardiointervalography indicators
    Study

    n = 30

    Comparator
    Controls
    Outcome group
    Autonomic function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared to the controls, significant positive changes in the indicators of HRV spectrum analysis and cardiointervalography as well as the reduction in neurological deficit in patients treated with cerebrolysin, which has neurotrophic and neuroprotective properties, was found.
    2 context sentences
    Summary · context
    To study the neurotrophic and neuroprotective effects of cerebrolysin on the autonomic homeostasis in patients with ischemic stroke (IS) using heart rate variability (HRV) method.
    Summary · context
    Thirty patients, 12 men and 18 women (mean age 65.0±7.8 years) in the acute stage of IS were enrolled in the study.
  3. 03HumanNon-randomized trialEfficacy outcome

    In patients with acute ischemic stroke, cerebrolysin treatment reduced neurological deficit compared with controls.

    In plain wordsIn patients with stroke, cerebrolysin reduced neurological deficits compared with controls.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseNeurological deficit
    Study

    n = 30

    Comparator
    Controls
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared to the controls, significant positive changes in the indicators of HRV spectrum analysis and cardiointervalography as well as the reduction in neurological deficit in patients treated with cerebrolysin, which has neurotrophic and neuroprotective properties, was found.
    2 context sentences
    Summary · context
    To study the neurotrophic and neuroprotective effects of cerebrolysin on the autonomic homeostasis in patients with ischemic stroke (IS) using heart rate variability (HRV) method.
    Summary · context
    Thirty patients, 12 men and 18 women (mean age 65.0±7.8 years) in the acute stage of IS were enrolled in the study.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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