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Study · Not a test of the peptide alone · 2015

7 results

Detection and in vitro metabolism of AOD9604.

Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D

Drug testing and analysis10 Sept 2014Cited by 11 (Europe PMC)

PMID25208511 (opens in a new tab)DOI10.1002/dta.1715 (opens in a new tab)PepBankPUB-25208511
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking AOD-9604.

  1. 01LabNot a test of AOD-9604 aloneIn vitro (cell-free)Other

    A solid-phase extraction method validated in urine detected AOD9604 with a limit of detection of 50 pg/mL.

    In plain wordsIn lab tests, a urine test method could detect AOD9604 at a very low level of 50 pg/mL.

    Peptide
    AOD-9604
    Outcome
    Not applicableUrine assay limit of detection
    Study

    n: not reported in source

    urine
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Limit of detection
    50 pg/mL
    urine

    Source sentences

    Summary
    To detect abuse of the peptide in athletes, a solid-phase extraction method was validated in urine with a limit of detection of 50 pg/mL.

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

  2. 02LabNot a test of AOD-9604 aloneIn vitro (cell-free)Other

    The validated urine method for AOD9604 had good linearity.

    In plain wordsIn lab tests, the urine test method for AOD9604 gave results in good proportion to the amount present.

    Peptide
    AOD-9604
    Outcome
    Not applicableAssay linearity
    Study

    n: not reported in source

    urine
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    The method has good linearity, precision (<20%), specificity and recovery (62%).

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

  3. 03LabNot a test of AOD-9604 aloneIn vitro (cell-free)Other

    The validated urine method for AOD9604 had a precision below 20%.

    In plain wordsIn lab tests, repeat measurements of AOD9604 in urine with the method varied by less than 20%.

    Peptide
    AOD-9604
    Outcome
    Not applicableAssay precision
    Study

    n: not reported in source

    urine
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Precision
    < 20%
    urine

    Source sentences

    Summary
    The method has good linearity, precision (<20%), specificity and recovery (62%).

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

  4. 04LabNot a test of AOD-9604 aloneIn vitro (cell-free)Other

    The validated urine method for AOD9604 had good specificity.

    In plain wordsIn lab tests, the urine test method for AOD9604 picked out the peptide well.

    Peptide
    AOD-9604
    Outcome
    Not applicableAssay specificity
    Study

    n: not reported in source

    urine
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    The method has good linearity, precision (<20%), specificity and recovery (62%).

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

  5. 05LabNot a test of AOD-9604 aloneIn vitro (cell-free)Other

    The solid-phase extraction method recovered 62% of AOD9604 from urine.

    In plain wordsIn lab tests, the urine test method recovered 62% of the AOD9604 present.

    Peptide
    AOD-9604
    Outcome
    Not applicableAssay recovery
    Study

    n: not reported in source

    urine
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Recovery
    62%
    urine

    Source sentences

    Summary
    The method has good linearity, precision (<20%), specificity and recovery (62%).

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

  6. 06LabNot a test of AOD-9604 aloneIn vitro (cell-free)Pharmacokinetics

    Six potential metabolites of AOD9604 were identified after incubation in serum and urine.

    In plain wordsIn lab tests, six possible breakdown products of AOD9604 were found after the peptide was kept in serum and urine.

    Peptide
    AOD-9604
    Outcome
    Not applicableMetabolites identified after incubation
    Study

    n: not reported in source

    serum and urine
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    Six potential metabolites of the peptide were identified after incubation of AOD9604 in serum and urine.

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

  7. 07LabNot a test of AOD-9604 aloneIn vitro (cell-free)Pharmacokinetics

    In serum, one AOD9604 metabolite (amino acids CRSVEGSCG) was significantly more stable than the other metabolites and the parent compound.

    In plain wordsIn lab tests, one breakdown product of AOD9604 stayed intact longer in serum than the other breakdown products and the peptide itself.

    Peptide
    AOD-9604
    Outcome
    Not applicableStability of metabolites in serum
    Study

    n: not reported in source

    serum
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    Quantification of the metabolites in serum identified a single metabolite, consisting of amino acids CRSVEGSCG, which is significantly more stable than the other metabolites or the parent compound.

    In this study, AOD-9604 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AOD-9604.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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