Skip to content

Study · Not a test of the peptide alone · 2014

1 result

Poly (D,L-lactide-co-glycolide) nanoparticles loaded with cerebrolysin display neuroprotective activity in a rat model of concussive head injury.

Ruozi B, Belletti D, Forni F, Sharma A, Muresanu D, Mössler H, Vandelli MA, Tosi G, Sharma HS

CNS & neurological disorders drug targets1 Jan 2014Cited by 19 (Europe PMC)

PMID25106629 (opens in a new tab)DOI10.2174/1871527313666140806145540 (opens in a new tab)PepBankPUB-25106629
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cerebrolysin.

  1. 01AnimalNot a test of Cerebrolysin aloneAnimal study (in vivo)Efficacy outcome

    In rats with concussive head injury, nanoparticle-loaded cerebrolysin had greater neuroprotective effects than free cerebrolysin.

    In plain wordsIn rats with head injury, nanoparticle-loaded cerebrolysin provided greater neuroprotection than free cerebrolysin.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseNeuroprotective effects
    Study

    ratn: not reported in source

    Concussive head injury
    Comparator
    Free cerebrolysin
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    Our results clearly show that delivery of CBL by NPs has superior neuroprotective effects following CHI as compared to normal CBL.
    2 context sentences
    Summary · context
    In this investigation, we compared the neuroprotective efficacy of poly-lactide-co-glycolide nanoparticles (NPs) loaded with CBL vs free CBL in a rat model of concussive head injury (CHI).
    Summary · context
    Free CBL or CBL loaded NPs was administered 30 min to 1 h after CHI and animals were sacrificed 5 h later.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.