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Study · Randomized controlled trial · 2015

1 result

Oxytocin increases empathy to pain when adopting the other- but not the self-perspective.

Abu-Akel A, Palgi S, Klein E, Decety J, Shamay-Tsoory S

Social neuroscience7 Aug 2014Cited by 56 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy adults, oxytocin increased empathy for pain when imagining others compared with imagining oneself, whereas placebo showed no difference between perspectives.

    In plain wordsIn healthy adults, oxytocin raised empathy for another person's pain more than for their own, while placebo showed no such difference.

    Peptide
    Oxytocin
    Outcome
    IncreaseEmpathy for pain, other-perspective vs self-perspective
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Under OT treatment, participants expressed more empathy when imagining others than when imagining oneself in pain.
    2 context sentences
    Summary · context
    This was in contrast to the placebo condition where there were no differences between the empathic responses during the self- and the other-perspective.
    Summary · context
    In this double-blind, placebo-controlled, within-subject crossover design, empathic responses of healthy participants were compared when imagining oneself (i.e., self-perspective empathy) versus when imagining the other (i.e., other-perspective empathy) in painful and nonpainful situations.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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