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Study · Animal study (in vivo) · rat · 2014

2 results

[Rat tissues antioxidant status correction by peptide delta sleep during physiological aging of the organism].

Bondarenko TI, Kutilin DS, Mikhaleva II

Advances in gerontology = Uspekhi gerontologii1 Jan 2014

PMID25051765 (opens in a new tab)PepBankPUB-25051765
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats aged 2 to 24 months, exogenous DSIP increased the glutathione antioxidant system level in tissues.

    In plain wordsIn rats, DSIP raised the level of an antioxidant system in tissues across ages.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseGlutathione antioxidant system level in rat tissues
    Study

    ratn: not reported in source

    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    100 mg/kg · subcutaneous · courses of 5 consecutive days per month, from 2 to 24 months of ageAs given in this study (rat).

    Source sentences

    Summary
    It is shown that exogenous delta-sleep inducing peptide increases glutathione antioxidant system level in rat tissues at different stages of ontogenesis, by subcutaneous injection to rats 2-24 months postnatal development in a dose of 100 mg/kg animal body weight by courses of 5 consecutive days per…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, the DSIP-induced increase of the glutathione antioxidant system was especially marked in non-renewable postmitotic tissues.

    In plain wordsIn rats, the antioxidant rise from DSIP was strongest in tissues whose cells do not renew.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseGlutathione antioxidant system in non-renewable postmitotic tissues
    Study

    ratn: not reported in source

    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    100 mg/kg · subcutaneous · courses of 5 consecutive days per month, from 2 to 24 months of ageAs given in this study (rat).

    Source sentences

    Summary
    this effect is especially marked in non-renewable postmitotic tissues.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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