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Study · Randomized controlled trial · 2014

2 results

Gender moderates the effect of oxytocin on social judgments.

Hoge EA, Anderson E, Lawson EA, Bui E, Fischer LE, Khadge SD, Barrett LF, Simon NM

Human psychopharmacology1 May 2014Cited by 46 (Europe PMC)

PMID24911580 (opens in a new tab)DOI10.1002/hup.2402 (opens in a new tab)PepBankPUB-24911580
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In male participants, intranasal oxytocin led to more negative ratings of faces than placebo in both tasks.

    In plain wordsIn men, oxytocin nasal spray led to more negative ratings of faces than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseSocial judgments of faces
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    In both tasks, we found that gender moderated the effect of oxytocin, such that male participants in the oxytocin condition rated faces more negatively, compared with placebo.
    1 context sentence
    Summary · context
    Forty-seven male and female participants made judgments of faces during two different tasks, after being randomized to either double-blinded intranasal oxytocin or placebo.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In female participants, intranasal oxytocin led to more positive ratings of faces than placebo.

    In plain wordsIn women, oxytocin nasal spray led to more positive ratings of faces than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseSocial judgments of faces
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    The opposite pattern of findings emerged for female participants: they rated faces more positively in the oxytocin condition, compared with placebo.
    1 context sentence
    Summary · context
    Forty-seven male and female participants made judgments of faces during two different tasks, after being randomized to either double-blinded intranasal oxytocin or placebo.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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