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Study · Not a test of the peptide alone · 2014

2 results

Short peptides stimulate serotonin expression in cells of brain cortex.

Khavinson VKh, Lin'kova NS, Tarnovskaya SI, Umnov RS, Elashkina EV, Durnova AO

Bulletin of experimental biology and medicine1 May 2014Cited by 5 (Europe PMC)

PMID24909721 (opens in a new tab)DOI10.1007/s10517-014-2496-y (opens in a new tab)PepBankPUB-24909721
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Pinealon.

  1. 01Computer modelNot a test of Pinealon aloneIn silicoMechanism

    Molecular docking indicated regulation of the 5-tryptophan hydroxylase gene by Glu-Asp-Arg.

    In plain wordsComputer models indicated that Pinealon could regulate a gene for an enzyme involved in serotonin synthesis.

    Peptide
    Pinealon
    Outcome
    Not applicablePredicted gene regulation
    Study

    n: not reported in source

    Molecular docking with the 5-tryptophan hydroxylase gene
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Peptide regulation of 5-tryptophan hydroxylase gene encoding the enzyme involved in serotonin synthesis was demonstrated by the molecular docking method.
    1 context sentence
    Summary · context
    Peptides Glu-Asp-Arg and Lys-Glu-Asp stimulate serotonin expression in aging cultures of brain cortex cells.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

  2. 02Computer modelNot a test of Pinealon aloneIn silicoMechanism

    Molecular docking identified CCTGCC in the 5-tryptophan hydroxylase gene as complementary to Glu-Asp-Arg.

    In plain wordsComputer models identified a gene sequence complementary to Pinealon.

    Peptide
    Pinealon
    Outcome
    Not applicableComplementary nucleotide sequence
    Study

    n: not reported in source

    Molecular docking with the 5-tryptophan hydroxylase gene
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The CCTGCC nucleotide sequence in 5-tryptophan hydroxylase gene was found to be complementary to these peptides.
    2 context sentences
    Summary · context
    Peptide regulation of 5-tryptophan hydroxylase gene encoding the enzyme involved in serotonin synthesis was demonstrated by the molecular docking method.
    Summary · context
    Peptides Glu-Asp-Arg and Lys-Glu-Asp stimulate serotonin expression in aging cultures of brain cortex cells.

    In this study, Pinealon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pinealon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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