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Study · Randomized controlled trial · n = 82 · 2014

3 results

The beneficial effect of oxytocin on avoidance-related facial emotion recognition depends on early life stress experience.

Feeser M, Fan Y, Weigand A, Hahn A, Gärtner M, Aust S, Böker H, Bajbouj M, Grimm S

Psychopharmacology29 May 2014Cited by 18 (Europe PMC)

PMID24871703 (opens in a new tab)DOI10.1007/s00213-014-3631-1 (opens in a new tab)PepBankPUB-24871703
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In male participants, oxytocin improved recognition of avoidance-related emotional faces compared with approach-related faces.

    In plain wordsIn men, oxytocin improved recognition of avoidance-related emotional faces more than approach-related faces.

    Peptide
    Oxytocin
    Outcome
    IncreaseRecognition of avoidance-related versus approach-related emotional faces
    Study

    n = 82

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Our results showed that OXT improved the ability to recognize avoidance-related emotional faces as compared to approach-related emotional faces.
    1 context sentence
    Summary · context
    In a double-blind, between-subjects, placebo-controlled design, 82 male participants performed an emotion recognition task with faces taken from the "Karolinska Directed Emotional Faces" set.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In male participants with lower early life stress scores, oxytocin enhanced emotion recognition compared with placebo.

    In plain wordsIn men with lower early life stress scores, oxytocin improved emotion recognition compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseAvoidance-related emotion recognition in participants with lower early life stress scores
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    OXT enhanced emotion recognition in participants with lower ELS scores.
    1 context sentence
    Summary · context
    In a double-blind, between-subjects, placebo-controlled design, 82 male participants performed an emotion recognition task with faces taken from the "Karolinska Directed Emotional Faces" set.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In male participants with higher early life stress scores, avoidance-related emotion recognition was comparable between oxytocin and placebo.

    In plain wordsIn men with higher early life stress scores, oxytocin and placebo gave similar emotion recognition.

    Peptide
    Oxytocin
    Outcome
    No significant changeAvoidance-related emotion recognition in participants with higher early life stress scores
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Whereas the performance for avoidance-related emotions in participants with higher ELS scores was comparable in both OXT and placebo condition
    1 context sentence
    Summary · context
    In a double-blind, between-subjects, placebo-controlled design, 82 male participants performed an emotion recognition task with faces taken from the "Karolinska Directed Emotional Faces" set.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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