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Study · Randomized controlled trial · n = 68 · 2014

3 results

Oxytocin improves emotion recognition for older males.

Campbell A, Ruffman T, Murray JE, Glue P

Neurobiology of aging26 Apr 2014Cited by 48 (Europe PMC)

PMID24856057 (opens in a new tab)DOI10.1016/j.neurobiolaging.2014.04.021 (opens in a new tab)PepBankPUB-24856057
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In young adults, oxytocin did not change emotion recognition relative to placebo.

    In plain wordsIn young adults, oxytocin nasal spray did not change recognition of facial emotions compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotion recognition accuracy
    Study

    n = 68

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    20 international units · nasal sprayAs given in this study (human).

    Source sentences

    Summary
    No differences were found for older females or young adults.
    1 context sentence
    Summary · context
    We examined this idea using a double-blind design, testing 68 older and 68 young adults randomly allocated to receive oxytocin nasal spray (20 international units) or placebo.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In older males, intranasal oxytocin improved emotion recognition relative to placebo.

    In plain wordsIn older men, oxytocin nasal spray improved recognition of facial emotions compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseEmotion recognition accuracy
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    20 international units · nasal sprayAs given in this study (human).

    Source sentences

    Summary
    Older males receiving oxytocin showed improved emotion recognition relative to those taking placebo.
    1 context sentence
    Summary · context
    We examined this idea using a double-blind design, testing 68 older and 68 young adults randomly allocated to receive oxytocin nasal spray (20 international units) or placebo.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In older females, oxytocin did not change emotion recognition relative to placebo.

    In plain wordsIn older women, oxytocin nasal spray did not change recognition of facial emotions compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotion recognition accuracy
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    20 international units · nasal sprayAs given in this study (human).

    Source sentences

    Summary
    No differences were found for older females or young adults.
    1 context sentence
    Summary · context
    We examined this idea using a double-blind design, testing 68 older and 68 young adults randomly allocated to receive oxytocin nasal spray (20 international units) or placebo.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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