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Study · Not a test of the peptide alone · 2014

1 result

Adiponectin is sufficient, but not required, for exercise-induced increases in the expression of skeletal muscle mitochondrial enzymes.

Ritchie IR, MacDonald TL, Wright DC, Dyck DJ

The Journal of physiology31 Mar 2014Cited by 14 (Europe PMC)

PMID24687585 (opens in a new tab)DOI10.1113/jphysiol.2014.273680 (opens in a new tab)PepBankPUB-24687585
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, AICAR (acadesine) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking AICAR (acadesine).

  1. 01LabNot a test of AICAR (acadesine) aloneEx vivo tissueActivity measurement

    In isolated mouse muscles, AICAR-stimulated palmitate oxidation was similar between adiponectin knockout and wild-type genotypes in both muscles.

    In plain wordsIn lab tests, AICAR-stimulated fat oxidation was similar in muscles from adiponectin knockout and wild-type mice.

    Peptide
    AICAR (acadesine)
    Outcome
    No significant changeAICAR-stimulated palmitate oxidation
    Study

    mousen: not reported in source

    isolated soleus and EDL muscles
    Comparator
    wild-type versus adiponectin knockout
    Outcome group
    Mitochondrial function · Metabolic and weight

    Source sentences

    Summary
    5-aminoimidazole-4-carboxamide (AICAR)-stimulated palmitate oxidation was similar in both genotypes regardless of muscle.

    In this study, AICAR (acadesine) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking AICAR (acadesine).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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