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Study · Animal study (in vivo) · rat · 2013

5 results

[Protective effect of selank on the model of mnestic function violation induced by pharmacological blockade of protein synthesis].

Kozlovskiĭ II, Belozertsev FIu, Andreeva LA, Kozlovskaia MM

Eksperimental'naia i klinicheskaia farmakologiia1 Jan 2013

PMID24605419 (opens in a new tab)PepBankPUB-24605419
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats given actinomycin D, selank prevented or compensated the impairment of memory acquisition.

    In plain wordsIn rats given a drug that impairs memory, selank prevented or made up for the loss of learning.

    Peptide
    Selank
    Outcome
    IncreaseAcquisition of memory under actinomycin D
    Study

    ratn: not reported in source

    Actinomycin D memory impairment, 16-door labyrinth
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Selank (0.5 mg/kg, i.p.) prevented or compensated for actinomycin D (250 mg/kg, i.p.) induced violation of the process of acquisition
    1 context sentence
    Summary · context
    The experiments were performed on white rats with acquired adaptive ability of spatial visual orientation in a 16-door labyrinth.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats given actinomycin D, selank prevented or compensated the impairment of memory improvement during a complex site reflex.

    In plain wordsIn rats given a drug that impairs memory, selank prevented or made up for the loss of memory improvement.

    Peptide
    Selank
    Outcome
    IncreaseImprovement of memory trace under actinomycin D
    Study

    ratn: not reported in source

    Actinomycin D memory impairment, 16-door labyrinth
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Selank (0.5 mg/kg, i.p.) prevented or compensated for actinomycin D (250 mg/kg, i.p.) induced violation of the process of acquisition, improvement, and consolidation of memory trace during the development of a complex site reflex
    1 context sentence
    Summary · context
    The experiments were performed on white rats with acquired adaptive ability of spatial visual orientation in a 16-door labyrinth.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats given actinomycin D, selank prevented or compensated the impairment of memory consolidation.

    In plain wordsIn rats given a drug that impairs memory, selank prevented or made up for the loss of memory consolidation.

    Peptide
    Selank
    Outcome
    IncreaseConsolidation of memory trace under actinomycin D
    Study

    ratn: not reported in source

    Actinomycin D memory impairment, 16-door labyrinth
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Selank (0.5 mg/kg, i.p.) prevented or compensated for actinomycin D (250 mg/kg, i.p.) induced violation of the process of acquisition, improvement, and consolidation of memory trace during the development of a complex site reflex
    1 context sentence
    Summary · context
    The experiments were performed on white rats with acquired adaptive ability of spatial visual orientation in a 16-door labyrinth.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats, selank reduced the time needed to acquire the adaptive ability of spatial visual orientation in the labyrinth.

    In plain wordsIn rats, selank shortened the time needed to learn to find the way in a maze.

    Peptide
    Selank
    Outcome
    DecreaseTime to acquire spatial visual orientation
    Study

    ratn: not reported in source

    Actinomycin D memory impairment, 16-door labyrinth
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    The drug administration also reduced the time required for acquisition of the adaptive ability of spatial visual orientation in the labyrinth
    1 context sentence
    Summary · context
    The experiments were performed on white rats with acquired adaptive ability of spatial visual orientation in a 16-door labyrinth.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In rats, selank restored the re-learning process that actinomycin D had disturbed, after a change in the alternation of escape sites.

    In plain wordsIn rats, selank restored the re-learning ability that a memory-impairing drug had disturbed.

    Peptide
    Selank
    Outcome
    IncreaseRe-learning after change of escape sites
    Study

    ratn: not reported in source

    Actinomycin D memory impairment, 16-door labyrinth
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    restored the actinomycin D violated process of re-learning upon a change in the alternation of escape sites under free-choice conditions.
    1 context sentence
    Summary · context
    The experiments were performed on white rats with acquired adaptive ability of spatial visual orientation in a 16-door labyrinth.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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