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Study · Not a test of the peptide alone · 2014

1 result

Ghrelin alleviates neuropathic pain through GHSR-1a-mediated suppression of the p38 MAPK/NF-κB pathway in a rat chronic constriction injury model.

Zhou CH, Li X, Zhu YZ, Huang H, Li J, Liu L, Hu Q, Ma TF, Shao Y, Wu YQ

Regional anesthesia and pain medicine1 Mar 2014Cited by 31 (Europe PMC)

PMID24513955 (opens in a new tab)DOI10.1097/aap.0000000000000050 (opens in a new tab)PepBankPUB-24513955
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Mechanism

    In rats with sciatic nerve constriction injury, [D-Lys]-GHRP‑6 could block the reported effects of ghrelin.

    In plain wordsIn rats with nerve injury, [D-Lys]-GHRP‑6 could block the effects seen with ghrelin alone.

    Peptide
    GHRP-6
    Outcome
    MixedBlockade of ghrelin effects
    Study

    ratn: not reported in source

    sciatic nerve chronic constriction injury
    Comparator
    ghrelin alone
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    In addition, the effect of ghrelin could be blocked by [D-Lys]-GHRP-6, a GHSR-1a antagonist.
    1 context sentence
    Summary · context
    A rat model of neuropathic pain was established by chronic constriction injury (CCI) of the sciatic nerve.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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