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Study · Randomized controlled trial · n = 106 · 2014

4 results

Oxytocin does not make a face appear more trustworthy but improves the accuracy of trustworthiness judgments.

Lambert B, Declerck CH, Boone C

Psychoneuroendocrinology1 Nov 2013Cited by 24 (Europe PMC)

PMID24485476 (opens in a new tab)DOI10.1016/j.psyneuen.2013.10.015 (opens in a new tab)PepBankPUB-24485476
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy participants, oxytocin did not change the average trustworthiness evaluation of artificial neutral faces compared with placebo.

    In plain wordsIn healthy people, oxytocin did not change how trustworthy neutral faces looked, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeAverage trustworthiness evaluation of neutral faces
    Study

    n = 106

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results indicate that oxytocin (relative to a placebo) does not affect the evaluation of trustworthiness in the first task.
    1 context sentence
    Summary · context
    In a double blind oxytocin/placebo experiment (N=106) participants conducted two judgement tasks.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy participants, oxytocin significantly reduced the misclassification of untrustworthy faces as trustworthy compared with placebo.

    In plain wordsIn healthy people, oxytocin led to fewer cases where untrustworthy faces were seen as trustworthy, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseMisclassification of untrustworthy faces as trustworthy
    Study

    n = 106

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, in the second task, misclassification of untrustworthy faces as trustworthy occurred significantly less in the oxytocin group.
    1 context sentence
    Summary · context
    In a double blind oxytocin/placebo experiment (N=106) participants conducted two judgement tasks.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy participants, oxytocin improved the ability to discriminate untrustworthy faces compared with placebo.

    In plain wordsIn healthy people, oxytocin helped them tell untrustworthy faces apart more accurately than placebo did.

    Peptide
    Oxytocin
    Outcome
    IncreaseDiscriminatory ability for untrustworthy faces
    Study

    n = 106

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Furthermore, oxytocin improved the discriminatory ability of untrustworthy, but not trustworthy faces.
    1 context sentence
    Summary · context
    In a double blind oxytocin/placebo experiment (N=106) participants conducted two judgement tasks.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In healthy participants, oxytocin did not improve the ability to discriminate trustworthy faces compared with placebo.

    In plain wordsIn healthy people, oxytocin did not help them tell trustworthy faces apart better than placebo did.

    Peptide
    Oxytocin
    Outcome
    No significant changeDiscriminatory ability for trustworthy faces
    Study

    n = 106

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Furthermore, oxytocin improved the discriminatory ability of untrustworthy, but not trustworthy faces.
    1 context sentence
    Summary · context
    In a double blind oxytocin/placebo experiment (N=106) participants conducted two judgement tasks.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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