[The results of the application of the pre-formed physical factors and neuroprotective therapy for the rehabilitative treatment of the patients with diabetic retinopathy].

Nazarova GA, Konchugova TV, Iurova OV, Turova EA, Rassulova MA, Sichinava NV, Morozova NE

Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury1 Sept 2013

PMID24437205PepBankPUB-24437205

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

01HumanNon-randomized trialEfficacy outcome
In patients with non-proliferative diabetic retinopathy, the two groups treated with semax showed positive dynamics of visual characteristics.
In plain wordsIn people with diabetic eye disease, visual measures improved in the two groups given semax.
Peptide
Semax
Outcome
IncreaseVisual function dynamics
Study
n: not reported in source
Outcome group
Vision and retina · Eye
Studied dose
0.1% · endonasal electrophoresis of 0.1% semax preparation or intranasal instillationAs given in this study (human).
Source sentences
Summary
The patients of the first two groups showed positive dynamics of the studied functional characteristics (visual, perimetric, and electrophysiological ones).
4 context sentences(design, population, supporting numbers)
Summary · context
The study included 114 patients (228 eyes) at the age varying from 42 to 70 who presented with diabetes mellitus and non-proliferative diabetic retinopathy.
Summary · context
Three groups were formed depending on the mode of treatment.
Summary · context
The patients in main group underwent endonasal electrophoresis of 0.1% semax preparation.
Summary · context
Patients of the comparison group were treated with intranasal instillations of semax and those of the control group received only standard hypoglycemic therapy and treatment with Doxy-Hem.
Report a problemFND-2443720501
02HumanNon-randomized trialEfficacy outcome
In patients with non-proliferative diabetic retinopathy, the two groups treated with semax showed positive dynamics of perimetric characteristics.
In plain wordsIn people with diabetic eye disease, visual field measures improved in the two groups given semax.
Peptide
Semax
Outcome
IncreasePerimetric characteristics dynamics
Study
n: not reported in source
Outcome group
Vision and retina · Eye
Studied dose
0.1% · endonasal electrophoresis of 0.1% semax preparation or intranasal instillationAs given in this study (human).
Source sentences
Summary
The patients of the first two groups showed positive dynamics of the studied functional characteristics (visual, perimetric, and electrophysiological ones).
4 context sentences(design, population, supporting numbers)
Summary · context
The study included 114 patients (228 eyes) at the age varying from 42 to 70 who presented with diabetes mellitus and non-proliferative diabetic retinopathy.
Summary · context
Three groups were formed depending on the mode of treatment.
Summary · context
The patients in main group underwent endonasal electrophoresis of 0.1% semax preparation.
Summary · context
Patients of the comparison group were treated with intranasal instillations of semax and those of the control group received only standard hypoglycemic therapy and treatment with Doxy-Hem.
Report a problemFND-2443720502
03HumanNon-randomized trialEfficacy outcome
In patients with non-proliferative diabetic retinopathy, the two groups treated with semax showed positive dynamics of electrophysiological characteristics.
In plain wordsIn people with diabetic eye disease, eye electrical measures improved in the two groups given semax.
Peptide
Semax
Outcome
IncreaseElectrophysiological characteristics dynamics
Study
n: not reported in source
Outcome group
Vision and retina · Eye
Studied dose
0.1% · endonasal electrophoresis of 0.1% semax preparation or intranasal instillationAs given in this study (human).
Source sentences
Summary
The patients of the first two groups showed positive dynamics of the studied functional characteristics (visual, perimetric, and electrophysiological ones).
4 context sentences(design, population, supporting numbers)
Summary · context
The study included 114 patients (228 eyes) at the age varying from 42 to 70 who presented with diabetes mellitus and non-proliferative diabetic retinopathy.
Summary · context
Three groups were formed depending on the mode of treatment.
Summary · context
The patients in main group underwent endonasal electrophoresis of 0.1% semax preparation.
Summary · context
Patients of the comparison group were treated with intranasal instillations of semax and those of the control group received only standard hypoglycemic therapy and treatment with Doxy-Hem.
Report a problemFND-2443720503
04HumanNon-randomized trialEfficacy outcome
In patients with non-proliferative diabetic retinopathy, the most pronounced and long-standing positive effect on visual function, up to 12 months, occurred in the group with endonasal semax electrophoresis.
In plain wordsIn people with diabetic eye disease, the best and longest-lasting visual improvement, up to 12 months, occurred with semax given by endonasal electrophoresis.
Peptide
Semax
Outcome
IncreaseVisual function, most pronounced and long-standing effect (up to 12 months) in the electrophoresis group
Study
n: not reported in source
Comparator
Intranasal semax instillation group and control group with standard therapy only
Outcome group
Vision and retina · Eye
Studied dose
0.1% · endonasal electrophoresis of 0.1% semax preparationAs given in this study (human).
Source sentences
Summary
The most pronounced and long-standing (up to 12 months) positive effect on the visual function was documented in the main group.
4 context sentences(design, population, supporting numbers)
Summary · context
The study included 114 patients (228 eyes) at the age varying from 42 to 70 who presented with diabetes mellitus and non-proliferative diabetic retinopathy.
Summary · context
Three groups were formed depending on the mode of treatment.
Summary · context
The patients in main group underwent endonasal electrophoresis of 0.1% semax preparation.
Summary · context
Patients of the comparison group were treated with intranasal instillations of semax and those of the control group received only standard hypoglycemic therapy and treatment with Doxy-Hem.
Report a problemFND-2443720504

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 17:28 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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