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Study · Measured the body's own peptide · 2014

1 result

Mechanical loading by fluid shear stress of myotube glycocalyx stimulates growth factor expression and nitric oxide production.

Juffer P, Bakker AD, Klein-Nulend J, Jaspers RT

Cell biochemistry and biophysics1 Jul 2014Cited by 47 (Europe PMC)

PMID24402674 (opens in a new tab)DOI10.1007/s12013-013-9812-4 (opens in a new tab)PepBankPUB-24402674
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In C2C12 myotubes, pulsating fluid flow shear stress increased the level of MGF mRNA.

    In plain wordsIn muscle cells in a lab dish, fluid flow raised the cells' own MGF gene activity.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA expression after pulsating fluid flow
    Study

    n: not reported in source

    C2C12 myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    PFF increased IGF-I Ea, MGF, VEGF, IL-6, and COX-2 mRNA
    2 context sentences
    Summary · context
    C2C12 myotubes were subjected to a laminar pulsating fluid flow (PFF; mean shear stress 0.4, 0.7 or 1.4 Pa, 1 Hz) or subjected to uni-axial cyclic strain (CS; 15 % strain, 1 Hz) for 1 h.
    Summary · context
    Gene expression was analyzed immediately after 1-h PFF (1.4 Pa, 1 Hz) and at 6 h post-PFF treatment.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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