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Study · In vitro (cells) · 2013

2 results

[Genome instability in pulmonary tuberculosis before and after treatment].

Dzhokhadze TA, Buadze TZh, Rubanov KD, Kiriia NA, Lezhava TA

Georgian medical news1 Nov 2013Cited by 1 (Europe PMC)

PMID24323970 (opens in a new tab)PepBankPUB-24323970
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In lymphocyte cultures from patients with pulmonary tuberculosis, epitalon reduced the mean frequency of cells with chromosome aberrations.

    In plain wordsIn lab cells from tuberculosis donors, epitalon lowered the share of cells with chromosome damage.

    Peptide
    Epitalon
    Outcome
    DecreaseChromosome aberration frequency with epitalon
    Study

    humann: not reported in source

    Mitogen-stimulated lymphocyte cultures from tuberculosis patients
    Outcome group
    Genome stability · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    As for epithalon, it appears that was shown a pronounced protective effect after treatment, on the test of chromosome aberrations, by reducing both overall mean frequency aberrant cells and indicators for all individuals.
    1 context sentence
    Summary · context
    The studies were conducted using short-term mitoge -stimulated cell cultures of TB patients, before and after treatment.
  2. 02LabIn vitro (cells)Efficacy outcome

    In lymphocyte cultures from patients with pulmonary tuberculosis, a high frequency of chromosome fragility persisted with the peptide bioregulator epitalon, before and after treatment.

    In plain wordsIn lab cells from tuberculosis donors, chromosome fragility stayed high when epitalon was added.

    Peptide
    Epitalon
    Outcome
    No significant changeChromosome fragile sites with epitalon
    Study

    humann: not reported in source

    Mitogen-stimulated lymphocyte cultures from tuberculosis patients
    Outcome group
    Genome stability · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    High frequency of chromosome fragility persisted by treatment with peptide bioregulator in both cases - before and after treatment.
    1 context sentence
    Summary · context
    The studies were conducted using short-term mitoge -stimulated cell cultures of TB patients, before and after treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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