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Study · Randomized controlled trial · n = 24 · 2014

2 results

The effects of oxytocin on social reward learning in humans.

Clark-Elford R, Nathan PJ, Auyeung B, Voon V, Sule A, Müller U, Dudas R, Sahakian BJ, Phan KL, Baron-Cohen S

The international journal of neuropsychopharmacology28 Oct 2013Cited by 23 (Europe PMC)

PMID24160414 (opens in a new tab)DOI10.1017/s1461145713001120 (opens in a new tab)PepBankPUB-24160414
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In typical male volunteers, oxytocin reduced performance of learning rewards from happy faces versus placebo.

    In plain wordsIn healthy men, oxytocin made learning rewards from happy faces worse than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseReward learning from happy faces
    Study

    n = 24

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Oxytocin selectively reduced performance of learning rewards, but not losses, from happy faces.
    1 context sentence
    Summary · context
    In a double-blind, randomised, placebo-controlled, within-group study design, 24 typical male volunteers were administered 24 IU of oxytocin or placebo and subsequently completed an affective reward learning task.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In typical male volunteers, oxytocin did not reduce learning of losses from happy faces versus placebo.

    In plain wordsIn healthy men, oxytocin did not make learning from losses worse than placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeLoss learning from happy faces
    Study

    n = 24

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    but not losses, from happy faces.
    1 context sentence
    Summary · context
    In a double-blind, randomised, placebo-controlled, within-group study design, 24 typical male volunteers were administered 24 IU of oxytocin or placebo and subsequently completed an affective reward learning task.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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