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Study · Measured the body's own peptide · 2010

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Time Course Change of IGF1/Akt/mTOR/p70s6k Pathway Activation in Rat Gastrocnemius Muscle During Repeated Bouts of Eccentric Exercise.

Ochi E, Ishii N, Nakazato K

Journal of sports science & medicine1 Jun 2010Cited by 13 (Europe PMC)

PMID24149682 (opens in a new tab)PMCIDPMC3761746 (opens in a new tab)PepBankPUB-24149682
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats, 5 and 10 sessions of eccentric exercise both increased natural MGF mRNA expression in gastrocnemius muscle compared with period-matched controls.

    In plain wordsIn rats, repeated exercise raised the body's own MGF mRNA in leg muscle compared with resting controls.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA in medial gastrocnemius after eccentric exercise
    Study

    ratn = 24

    Eccentric exercise, medial gastrocnemius muscle
    Comparator
    Sham-operated control
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    The expression of MGF mRNA in both ECC5S and ECC10S were significantly higher than that in each period-matched control (p < 0.01).
    2 context sentences
    Summary · context
    Male Wistar rats (n = 24) were randomly assigned to 1 of the 2 groups: eccentric exercise (ECC) group or sham-operated control (CON) group.
    Summary · context
    Rats in the ECC group were trained every second day for 10 days (5 sessions in total) or 20 days (10 sessions in total).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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