In patients with small bowel and pancreatic neuroendocrine tumours, OXTR mRNA was overexpressed in primary and metastatic tumours compared with normal tissue.
In plain wordsIn tumour samples from patients, the oxytocin receptor gene was more active than in normal tissue. No oxytocin was given.
- Peptide
- Oxytocin
- Outcome
- IncreaseOXTR mRNA expression in primary and metastatic SBNETs and PNETs
- Study
n: not reported in source
- Comparator
- Normal tissue
- Outcome group
- Receptor activity and mechanism · Cancer
Source sentences
Compared to normal tissue, the oxytocin receptor (OXTR) showed significant overexpression in both primary and metastatic SBNETs and PNETs.
1 context sentence(design, population, supporting numbers)
Primary SBNETs and PNETs, normal tissue, nodal, and liver metastases were collected and mRNA expression of six target genes was determined by quantitative PCR.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.